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Table 4 Univariate and Multivariate Analyses of Factors Associated With Survival and Recurrence

From: Zinc finger protein ZBTB20 expression is increased in hepatocellular carcinoma and associated with poor prognosis

Factor

OS

DFS

  

Multivariate

 

Multivariate

 

Univariate P

Hazard Ratio

95% CI

P

Univariate P

Hazard Ratio

95% CI

P

Age: ≤ 50 v >50 years

0.603

  

NA

0.782

  

NA

Sex: female v male

0.197

  

NA

0.254

  

NA

Liver cirrhosis: no v yes

0.932

  

NA

0.194

  

NA

Tumor size: ≤ 50 v >50 mm

0.001

2.727

1.326-5.605

0.006

0.001

2.175

1.22-3.875

0.008

AFP: ≤ 20 v >20 ng/ml

0.051

  

NA

0.070

  

NS

HBsAg: positive v negative

0.141

  

NA

0.042

  

NS

TNM stage: I-II v III

0.002

  

NS

Ï…0.0001

1.982

1.288-3.366

0.005

Tumor number: single v multiple

0.017

  

NS

0.0001

  

NS

Tumor encapsulation: complete v uncomplete v no

0.051

  

NA

0.065

  

NA

Vein invasion: yes v no

0.001

1.713

0.927-3.167

0.086

Ï…0.0001

  

NS

Intratumoral ZBTB20: low v high

0.001

1.952

1.134-3.359

0.016

0.0000

2.094

1.296-3.383

0.003

Peritumoral ZBTB20: low v high

0.225

  

NA

0.002

  

NS

  1. Abbreviations: OS, overall survival; DFS, disease-free survival; NA, not adopted; HBsAg, hepatitis B s antigen; NS, not significant.