Figure 5
Evaluation of Lung Injury, Inflammation and Blood Oxygenation Levels in mice 4 months post-XRT. Mice were fed with 0% or 10%FS diet at designated times (-3, 0, +2, +4, +6 weeks) of X-ray radiation therapy (XRT). Data is represented mean ± SEM of two independent experiments (n = 15-25 mice per group). Panel A: Total WBC counts in bronchoalveolar lavage (BAL) of irradiated (13.5 Gy, XRT) mice after 4 months. *p ≤ 0.05 for irradiated 0%FS vs. irradiated 10%FS Panel B: Total proteins in BAL of mice after 4 months. *p ≤ 0.01 for irradiated 0%FS vs. irradiated 10%FS Panel C: Arterial O2 levels were measured using pulse oximetry in irradiated (13.5 Gy, XRT) mice after 4 months. The white, black, gray and hatched bars represent untreated control, 0%FS + XRT, 10%FS and 10%FS + XRT groups, respectively. *p ≤ 0.05 for irradiated 0%FS vs. irradiated 10%FS.