Skip to main content

Table 8 Significant alterations in expression of transcription factors and cell signaling factors in normal colon mucosa from patients with tumors of high intrinsic COX-2 expression

From: COX-2 gene expression in colon cancer tissue related to regulating factors and promoter methylation status

Gene Product FC 1.5 FC 2.0 FC 3.0
PTGS2 COX-2
Transcription     
ATF3 ATF3/AP1 - -
CEBPD C/EBP-δ -
CREB1 CREB - -
FOSB Fos-B/AP1 -
DNAJC12 JDP1 - -
NFATC1 NFATc1/NFAT2 - -
PPARG PPARγ - -
BATF B-ATF - -
External cell factors    
IL1B IL1b
IL6 IL6
NOS2A iNOS
  1. All factors listed in Table 6 and 7 were evaluated.