Figure 5
From: SIP1 is downregulated in hepatocellular carcinoma by promoter hypermethylation
In silico analysis of CpG-rich putative SIP1 promoters. The 100 Kb genomic region upstream of the third exon is analyzed by CpG island prediction (MethPrimer) and promoter prediction (Promoter2.0) programs. Localization of the CpG islands (gray zones) and three putative promoter (P1-P3) regions are represented. Boxes indicate the first and second exons and the translation start site of SIP1.