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Figure 1 | BMC Cancer

Figure 1

From: Adaptation to HIF-1 deficiency by upregulation of the AMP/ATP ratio and phosphofructokinase activation in hepatomas

Figure 1

Growth and FDG uptake characteristics of Hepa-1 c4 and WT tumours. A. Comparison of growth rate from Hepa-1 c4 and WT tumours. The Hepa-1 c4 () tumours had a slower growth rate compared with the WT (□) tumours and growth rates were significantly different at days 17, 21 and 24 (p < 0.05) (n = 10) but not at 28 days (p > 0.1). B. The uptake of FDG in Hepa-1 c4 () and WT (□) tumours measured by 18FDG -PET. Data were expressed as standardised uptake (SUV) (n = 4-6). For details see Methods. C. The uptake of 19FDG measured by 19F MRS in Hepa-1 c4 () and WT (□) tumours.

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