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Table 2 Patient characteristics at second radiation course.

From: Re-surgery and chest wall re-irradiation for recurrent breast cancer - a second curative approach

Characteristic at diagnosis of recurrence

Value

Patients (n)

42

Age (y)

 

   Median

57

   Range

33-75

Time to first recurrence (months)

 

   Median

33

   Range

9-400

Number of recurrences until re-irradiation

 

   1

23

   2

13

   more than 2 (range)

6 (3-5)

Site of recurrence (n)

 

   Chest wall

31

   In-breast recurrence

8

   Regional nodal

3

Surgery of recurrence preceeding re-irradiation (n)

 

   Mastectomy

9*

   Local excision

22

   Inoperable

11

pR-status for operable patients (n)

 

   R0

14

   R1

16

   R2

1

Re-Radiation treatment of recurrence

 

   Total radiation chest wall dose (Gy)

 

Median dose

60

Range

45-66

   Lymph node irradiation (n)

15#

   Cumulative radiation dose (Gy)

 

Median dose

110

Range

85-126

   Concurrent hyperthermia (n)

29

   Photons (n)

24

   Electrons (n)

18

Time between both radiation courses (months)

 

   Median

53

   Range

12-401

Systemic treatment of recurrent breast cancer (n)

 

   Sequential chemotherapy

17

   Hormonal treatment

19

  1. *15 Salvage mastectomies were performed at first recurrence explaining the lower number of mastectomies at time of re-irradiation.
  2. #Lymph node irradiation was normally restricted to sites initially not irradiated, i.e. axillary nodes.