From: Re-surgery and chest wall re-irradiation for recurrent breast cancer - a second curative approach
Characteristic at diagnosis of recurrence | Value |
---|---|
Patients (n) | 42 |
Age (y) | |
Median | 57 |
Range | 33-75 |
Time to first recurrence (months) | |
Median | 33 |
Range | 9-400 |
Number of recurrences until re-irradiation | |
1 | 23 |
2 | 13 |
more than 2 (range) | 6 (3-5) |
Site of recurrence (n) | |
Chest wall | 31 |
In-breast recurrence | 8 |
Regional nodal | 3 |
Surgery of recurrence preceeding re-irradiation (n) | |
Mastectomy | 9* |
Local excision | 22 |
Inoperable | 11 |
pR-status for operable patients (n) | |
R0 | 14 |
R1 | 16 |
R2 | 1 |
Re-Radiation treatment of recurrence | |
Total radiation chest wall dose (Gy) | |
Median dose | 60 |
Range | 45-66 |
Lymph node irradiation (n) | 15# |
Cumulative radiation dose (Gy) | |
Median dose | 110 |
Range | 85-126 |
Concurrent hyperthermia (n) | 29 |
Photons (n) | 24 |
Electrons (n) | 18 |
Time between both radiation courses (months) | |
Median | 53 |
Range | 12-401 |
Systemic treatment of recurrent breast cancer (n) | |
Sequential chemotherapy | 17 |
Hormonal treatment | 19 |