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Figure 3 | BMC Cancer

Figure 3

From: Major histocompatibility complex class I-related chain A/B (MICA/B) expression in tumor tissue and serum of pancreatic cancer: Role of uric acid accumulation in gemcitabine-induced MICA/B expression

Figure 3

Analysis of serum MICA levels in pancreatic cancer patients. (A) Increased serum sMICA levels were not associated with patient survival. Kaplan-Meier survival curves in 16 patients with serum MICA levels < 200 pg/ml and in 45 patients with serum MICA levels > 200 pg/ml were compared. (B) Serum sMICA levels were elevated in pancreatic cancer patients treated with gemcitabine. Blood samples collected from 10 patients before (Day 0) and after gemcitabine treatment at the indicated days were analyzed for serum MICA levels using a sandwich ELISA kit. A standard curve of the logarithimic relationship between concentration and absorbance was used to calculate serum MICA concentrations. Data from four patients whose serum MICA levels were undetectable before and after gemcitabine treatment are not shown.

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BMC Cancer

ISSN: 1471-2407

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