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Figure 2 | BMC Cancer

Figure 2

From: Major histocompatibility complex class I-related chain A/B (MICA/B) expression in tumor tissue and serum of pancreatic cancer: Role of uric acid accumulation in gemcitabine-induced MICA/B expression

Figure 2

MICA/B expression in pancreatic cancer by IHC analysis. The sections of pancreatic adenocarcinomas were analyzed for MICA/B expression by immunohistochemical staining with a monoclonal antibody (Clone SR99) (30 μg/ml) (A-C) or a polyclonal anti-MICA rabbit IgG (1:60) (E-F). Lack of MICA/B expression in normal pancreatic ductal epithelial cells (A) and a cyst adenocarcinoma (B). Mouse IgG isotype was included as a negative control (D). (C & E) MICA/B signals in the membrane and cytoplasm. (F) No signal was present in a MICA/B-negative pancreatic cancer.

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