Literature survey on epidemiology and pathology of gangliocytic paraganglioma

BMC Cancer

Table 4 Comparison of clinicopathological findings between GP within and exceeding the submucosal layer.

	Gangliocytic paraganglioma within the submucosal layer	Gangliocytic paraganglioma exceeding the submucosal layer	Statistical analysis
Number of patients	42	66
Age (years)	28 to 84 (mean: 54.1)	15 to 73 (mean: 50.0)	No significant difference was found (Mann-Whitney U test: p = 0.23)
Maximum diameter of the tumor (mm)	5.5 to 65 (mean: 21.7)	10 to 100 (mean: 26.8)	No significant difference was found (Mann-Whitney U test: p = 0.18)
Gender (male to female)	29:13	30:36	Significant difference was found (Chi-square test: p = 0.02)
Rate of lymph node metastasis	2.4% (1/42)	16.7% (11/66)	Significant difference was found (Chi-square test: p = 0.03)

Significant differences were found for gender and the rate of lymph node metastasis between patients with GP within the submucosal layer and exceeding the submucosal layer (Chi-square test: p = 0.02, 0.03, respectively).

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