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Table 2 Distribution of EGFR somatic mutation's frequency from lung adenocarcinoma tissues and transbronchial biopsies, depending on gender and smoking condition

From: Germ-line mutations in epidermal growth factor receptor (EGFR) are rare but may contribute to oncogenesis: A novel germ-line mutation in EGFR detected in a patient with lung adenocarcinoma

  

EGFR mutations

Sex

Smoking status

Exon 19

Exon 20

Exon 21

Male (n = 55)

Yes (n = 47)

 

1 (p.R776G)

1 (p.L858R)

 

No (n = 8)

2 (p.E746_A750del)

1 (p.E746_S752del)

 

1 (p.L858R)

Female (n = 16)

Yes (n = 7)

1 (p.E746_A750del)

  
 

No (n = 9)

2 (p.E746_T751del)

1 (p.E746_S752delinsV)

1 (p.D761_E762insEAFQ)

2 (p.L858R)

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BMC Cancer

ISSN: 1471-2407

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