Parameter | Â | Multivariate Analysis | ||
---|---|---|---|---|
 |  | P -value | HR | 95%CI |
Gender | Male | 0.622 | 1.199 | 0.582-2.473 |
 | Female |  | 1 |  |
Age | <65 | 0.215 | 1.569 | 0.770-3.199 |
 | ≥65 |  | 1 |  |
Histology | Intestinal type adenocarcinoma | 0.150 | 0.415 | 0.126-1.373 |
 | Mucinous carcinoma | 0.588 | 0.752 | 0.268-2.106 |
 | Signet-ring cell |  | 1 |  |
Differentiation | G1, G2 | 0.492 | 0.761 | 0.350-1.658 |
 | G3 |  | 1 |  |
Metastatic site | Dissemination | 0.516 | 1.387 | 0.578-3.437 |
 | Local |  | 1 |  |
Stage of disease | III c | 0.025 | 0.273 | 0.088-0.849 |
 | IV |  | 1 |  |
MMP-11 protein level | High level | 0.018 | 2.618 | 1.288-5.320 |
 | Low level |  | 1 |  |