Table 3 Promoter methylation of individual genes in NSCLC - multivariable models assessing PIK3CA amplification, smoking history, histologic type, and lymph node metastasis (OR^† and 95%CI)

2.55 (0.81-8.08)

1.08 (0.41-2.84)

1.46 (0.51-4.16)

1.38 (0.44-4.31)

0.42 (0.16-1.12)

1.35 (0.52-3.47)

4.01 (1.37-11.79)*

0.64 (0.24-1.75)

0.59 (0.11-3.15)

1.45 (0.39-5.30)

6.09 (1.25-29.66)*

2.26 (0.24-21.44)

1.31 (0.47-3.69)

0.94 (0.36-2.43)

2.06 (0.73-5.84)

0.92 (0.32-2.65)

0.19 (0.06-0.62)*

0.97 (0.31-3.11)

2.62 (0.68-10.14)

0.62 (0.19-2.05)

1.63 (0.57-4.70)

0.65 (0.22-1.95)

0.32 (0.09-1.18)

0.67 (0.24-1.87)