Keratin 23, a novel DPC4/Smad4 target gene which binds 14-3-3ε

BMC Cancer

Table 1 Smad4 target proteins identified by DIGE coupled with MALDI-TOF-MS

Spot No	Accession No	Protein	Profound Score	Sequence coverage	No. of Peptides
					matched	detected
1	gi\|44890631	tumor rejection antigen (gp96) 1	2.4	14.6	15	21
3	gi\|5031755	heterogeneous nuclear ribonucleoprotein R	2.5	23.4	12	20
4	gi\|181573	cytokeratin 8	2.4	29.0	11	15
6	gi\|4506439	retinoblastoma binding protein 7	2.4	26.4	12	20
7	gi\|4503471	eukaryotic translation elongation factor 1 alpha 1	1.0	12.6	6	13
8	gi\|4503471	eukaryotic translation elongation factor 1 alpha 1	1.8	20.3	8	20
9	gi\|4503471	eukaryotic translation elongation factor 1 alpha 1	1.3	18.8	6	20
10	gi\|27894339	cytokeratin 23	2.4	60.2	26	47
11	gi\|27894339	cytokeratin 23	2.2	34.4	17	26
15	gi\|30311	cytokeratin 18	2.4	22.9	12	21
16	gi\|1633054	cyclophilin A	2.2	48.2	12	23
17	gi\|1633054	cyclophilin A	1.6	51.2	7	20

Only spots with unequivocal identification by MALDI-TOF-MS are included in this table.

ISSN: 1471-2407