Skip to main content

Table 6 The comparisons of EORTC QLQ-C30 and H&N35 scales for head and neck cancer survivors by different RT techniques

From: Health-related Quality of life in 640 head and neck cancer survivors after radiotherapy using EORTC QLQ-C30 and QLQ-H&N35 questionnaires

  2DRT
(n = 371)
3DCRT
(n = 127)
IMRT
(n = 142)
 
  Mean (SD) Mean (SD) Mean (SD) p
EORTC QLQ-C30     
   Global quality of life 51.7 (19.9) 56.2 (18.6) 60.7 (19.7)b, <0.01
   Physical functioning 83.1 (17.7) 86.2 (14.1) 86.7 (14.6)b 0.039
   Role functioning 85.6 (22.2) 86.7 (19.4) 88.1 (19.1) NS
   Emotional functioning 76.6 (20.8) 79.8 (18.0) 79.6 (19.8) NS
   Cognitive functioning 77.2 (20.7) 79.9 (16.6) 80.0 (20.1) NS
   Social functioning 73.4 (26.0) 76.7 (20.3) 78.1 (22.0) NS
   Fatigue 31.0 (21.1) 26.9 (16.8) 26.5 (21.0) NS
   Nausea/Vomiting 10.3 (19.2) 7.7 (13.6) 8.2 (15.5) NS
   Pain 23.9 (24.1) 18.5 (16.9) 19.7 (21.7) NS
   Dyspnea 16.2 (23.4) 15.8 (18.8) 12.1 (18.7) NS
   Insomnia 26.9 (27.5) 25.6 (22.1) 25.4 (25.0) NS
   Appetite loss 21.7 (26.7) 18.8 (20.9) 16.4 (21.2) NS
   Constipation 19.8 (25.2) 19.2 (22.5) 17.1 (20.4) NS
   Diarrhea 14.8 (21.3) 12.4 (17.8) 13.3 (17.6) NS
   Financial problems 27.1 (28.1) 23.1 (24.1) 27.6 (26.7) NS
EORTC QLQ-HN35     
   Pain 20.8 (22.6) 18.4 (16.7) 15.2 (17.7) NS
   Swallowing 33.3 (25.6) 28.0 (22.4) 23.9 (21.5)b <0.01
   Senses (taste/smell) 29.4 (29.0) 26.3 (28.1) 20.6 (22.7)b <0.01
   Speech 29.6 (26.4) 29.5 (25.7) 22.4 (24.0)b 0.013
   Social eating 31.0 (27.5) 28.5 (27.0) 21.9 (24.3)b <0.01
   Social contact 21.0 (24.1) 22.7 (24.7) 16.6 (20.3)b <0.01
   Sexuality 27.4 (28.9) 27.0 (28.0) 21.5 (23.8) NS
   Teeth 43.2 (30.6) 34.7 (29.1)a 31.2 (26.0)b <0.01
   Opening mouth 36.5 (31.7) 30.2 (30.4) 25.4 (31.1)b <0.01
   Dry mouth 54.0 (31.9) 43.8 (28.2)a 41.0 (27.9)b <0.01
   Sticky saliva 45.1 (32.3) 35.8 (26.1)a 33.6 (27.9)b <0.01
   Coughing 31.0 (26.9) 29.5 (24.2) 24.5 (21.7) NS
   Feeling ill 32.3 (26.3) 26.3 (23.0) 24.0 (23.2)b <0.01
  1. Abbreviations: RT = radiotherapy; 2DRT = two dimensional RT; 3DCRT = three dimensional conformal RT; IMRT = intensity-modulated RT; a: p < 0.05, 3DCRT compared with 2DRT; b: p < 0.05, IMRT compared with 2DRT