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Table 4 Multiple linear regression analysis for global quality of life and xerostomia

From: Health-related Quality of life in 640 head and neck cancer survivors after radiotherapy using EORTC QLQ-C30 and QLQ-H&N35 questionnaires

 

Xerostomia

Global quality of life

Variable

β

SE

p

β

SE

p

Sociodemographic variables

      

Age: <40 v 40~60 v ≥60 years

-0.7

2.5

NS

-0.2

1.6

NS

Gender: female v male

-1.7

3.5

NS

0.5

2.2

NS

Education years: ≤ 6 v 6~12 v >12

1.2

3.6

NS

3.2

1.3

NS

Marital status: with v without spouse

-2.6

3.1

NS

-3.0

2.0

NS

Annual family income: <1.2 v ≥1.2 (million NTD)

-4.0

2.5

NS

5.2

1.6

<0.01

Clinical variables

      

CCI score: 0 v ≥ 1

5.2

2.5

0.034

-6.1

1.6

<0.01

Tumor site: Nasopharynx v others

-9.1

4.3

0.036

-0.9

2.7

NS

AJCC stage: stage I-II v III-IV

1.5

3.1

NS

0.2

2.0

NS

Treatment methods: S + RT v S + RT+ C/T v RT±C/T

3.0

3.7

NS

-1.8

2.3

NS

RT technique: 2DRT v 3DCRT/IMRT

-12.2

2.7

<0.01

7.7

1.7

<0.01

Follow-up years: 2~3 v 3~5 v > 5

0.2

2.9

NS

1.6

1.9

NS

  1. β: un-standardized regression coefficient; SE: standard error; R2 = 0.072 in the model for xerostomia; R2 = 0.077 in the model for global quality of life; NTD: New Taiwan Dollar (1 USD = 33 NTD); CCI: Charlson comorbidity index; AJCC: American Joint of Cancer Committee published in 2002; S: surgery; RT: radiotherapy; C/T: chemotherapy; 2DRT: two dimensional RT; 3DCRT: three dimensional conformal RT; IMRT: intensity modulated RT; NS: not significant.