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Table 4 Multiple linear regression analysis for global quality of life and xerostomia

From: Health-related Quality of life in 640 head and neck cancer survivors after radiotherapy using EORTC QLQ-C30 and QLQ-H&N35 questionnaires

  Xerostomia Global quality of life
Variable β SE p β SE p
Sociodemographic variables       
Age: <40 v 40~60 v ≥60 years -0.7 2.5 NS -0.2 1.6 NS
Gender: female v male -1.7 3.5 NS 0.5 2.2 NS
Education years: ≤ 6 v 6~12 v >12 1.2 3.6 NS 3.2 1.3 NS
Marital status: with v without spouse -2.6 3.1 NS -3.0 2.0 NS
Annual family income: <1.2 v ≥1.2 (million NTD) -4.0 2.5 NS 5.2 1.6 <0.01
Clinical variables       
CCI score: 0 v ≥ 1 5.2 2.5 0.034 -6.1 1.6 <0.01
Tumor site: Nasopharynx v others -9.1 4.3 0.036 -0.9 2.7 NS
AJCC stage: stage I-II v III-IV 1.5 3.1 NS 0.2 2.0 NS
Treatment methods: S + RT v S + RT+ C/T v RT±C/T 3.0 3.7 NS -1.8 2.3 NS
RT technique: 2DRT v 3DCRT/IMRT -12.2 2.7 <0.01 7.7 1.7 <0.01
Follow-up years: 2~3 v 3~5 v > 5 0.2 2.9 NS 1.6 1.9 NS
  1. β: un-standardized regression coefficient; SE: standard error; R2 = 0.072 in the model for xerostomia; R2 = 0.077 in the model for global quality of life; NTD: New Taiwan Dollar (1 USD = 33 NTD); CCI: Charlson comorbidity index; AJCC: American Joint of Cancer Committee published in 2002; S: surgery; RT: radiotherapy; C/T: chemotherapy; 2DRT: two dimensional RT; 3DCRT: three dimensional conformal RT; IMRT: intensity modulated RT; NS: not significant.