Table 3 GLM-MANOVA test of the overall effect of the sociodemographic and clinical variables on the EORTC QLQ-C30 and H&N35 scales

Sociodemographic variables

Age: <40 v 40~60 v ≥ 60 years

0.922

0.016

0.942

NS

0.926

0.013

0.939

NS

Gender: female v male

0.890

<0.01

0.877

<0.01

0.919

0.018

0.963

NS

Education years: ≤ 6 v 6~12 v >12

0.914

0.011

0.928

NS

0.920

0.033

0.941

NS

Marital status: with v without spouse

0.958

0.042

0.951

NS

0.975

NS

0.968

NS

Annual family income: < 0.6 v 0.6~1.2 v ≥ 1.2 (million NTD)

0.845

<0.01

0.896

0.032

0.866

<0.01

0.910

NS

Clinical variables

CCI score: 0 v ≥ 1

0.937

0.001

0.910

NS

0.965

NS

0.935

NS

Tumor site: Oral cavity v Oropharynx v Hypopharynx/Larynx v Nasopharynx

0.805

<0.01

0.828

<0.01

0.618

<0.01

0.824

<0.01

AJCC stage: stage I-II v III-IV

0.870

<0.01

0.863

<0.01

0.880

<0.01

0.869

NS

Treatment methods: S + RT v S + RT+ C/T v RT±C/T

0.865

<0.01

0.845

<0.01

0.832

<0.01

0.906

NS

RT technique: 2DRT v 3DCRT v IMRT

0.888

<0.01

0.876

<0.01

0.869

<0.01

0.829

<0.01

Follow-up years: 2~3 v 3~5 v > 5

0.937

NS

0.928

NS

0.933

NS

0.938

NS