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Table 2 Correlations between CAIX expression and clinicopathological factors.

From: Carbonic anhydrase IX in tumor tissue and sera of patients with primary cervical cancer

   Carbonic anhydrase IX expression p-value
   none/weak moderate/strong  
All samples (n = 221)   84 137  
Histological subtype (n = 221) squamous 53 108 0.024
  adenomatous 20 15  
  adenosquamous 11 14  
FIGO stage (n = 221) I 62 74 0.013
  II 15 46  
  III/IV 7 17  
UICC tumor stage (n = 221) pT1 65 76 0.001
  pT2 15 55  
  pT3/4 4 6  
Nodal involvement (n = 221) pN0 69 99 0.106
  pN1 15 38  
Number of positive lymphnodes (n = 221) 0 69 99 0.047
  1-3 13 23  
  >3 2 15  
Tumor grade (n = 215) G1 9 0 <0.001
  G2 32 63  
  G3 39 72  
Lymphovascular space invasion (n = 196) L0 25 39 0.875
  L1 49 83  
Invasion depth in mm (n = 185)* median 12 (n = 70) 16 (n = 115) 0.025
Patients age in years (n = 221)* median 49.5 47.0 0.549
SCC-Ag in μg/L (n = 144)* median 1 (n = 55) 1.9 (n = 89) 0.042
Serum CAIX in pg/mL (n = 46)* median 91 (n = 17) 110 (n = 29) 0.466
  1. Fisher's exact test was used for categorical data, the Mann-Whitney-U-Test for continuous variables (*).