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Table 2 Correlations between CAIX expression and clinicopathological factors.

From: Carbonic anhydrase IX in tumor tissue and sera of patients with primary cervical cancer

  

Carbonic anhydrase IX expression

p-value

  

none/weak

moderate/strong

 

All samples (n = 221)

 

84

137

 

Histological subtype (n = 221)

squamous

53

108

0.024

 

adenomatous

20

15

 
 

adenosquamous

11

14

 

FIGO stage (n = 221)

I

62

74

0.013

 

II

15

46

 
 

III/IV

7

17

 

UICC tumor stage (n = 221)

pT1

65

76

0.001

 

pT2

15

55

 
 

pT3/4

4

6

 

Nodal involvement (n = 221)

pN0

69

99

0.106

 

pN1

15

38

 

Number of positive lymphnodes (n = 221)

0

69

99

0.047

 

1-3

13

23

 
 

>3

2

15

 

Tumor grade (n = 215)

G1

9

0

<0.001

 

G2

32

63

 
 

G3

39

72

 

Lymphovascular space invasion (n = 196)

L0

25

39

0.875

 

L1

49

83

 

Invasion depth in mm (n = 185)*

median

12 (n = 70)

16 (n = 115)

0.025

Patients age in years (n = 221)*

median

49.5

47.0

0.549

SCC-Ag in μg/L (n = 144)*

median

1 (n = 55)

1.9 (n = 89)

0.042

Serum CAIX in pg/mL (n = 46)*

median

91 (n = 17)

110 (n = 29)

0.466

  1. Fisher's exact test was used for categorical data, the Mann-Whitney-U-Test for continuous variables (*).
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BMC Cancer

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