Table 2 Patient, tumour, and treatment characteristics in relation to time interval to and mode of detection of the second breast cancer
From: Prediction of outcome after diagnosis of metachronous contralateral breast cancer
Time interval to second breast cancer | Mode of detection of second breast cancer a | |||||||
|---|---|---|---|---|---|---|---|---|
First breast cancer, No (%) | Second breast cancer, No (%) | First breast cancer, No (%) | Second breast cancer, No (%) | |||||
<3 years | ≥3 years | <3 years | ≥3 years | Symptomatic | Asymptomatic | Symptomatic | Asymptomatic | |
No = 200 | No = 523 | No = 200 | No = 523 | No = 250 | No = 424 | No = 250 | No = 424 | |
Diagnosis of BC2 | ||||||||
<1977 | 1 (1) | 133 (25) | 0 | 0 | 70 (28) | 55 (13) | 0 | 0 |
1977-1986 | 59 (30) | 168 (32) | 48 (24) | 100 (19) | 77 (31) | 132 (31) | 57 (23) | 79 (19) |
1987-1996 | 84 (42) | 186 (36) | 80(40) | 177 (34) | 84 (34) | 174 (41) | 89 (36) | 150 (35) |
1997-2007 | 56 (28) | 36 (7) | 72 (36) | 246 (47) | 19 (8) | 63 (15) | 104 (42) | 195 (46) |
Age | ||||||||
Median (range) | 59 (39-89) | 57 (27-90) | 60 (32-91) | 69 (36-98) | 54 (27-89) | 59 (30-87) | 66 (35-97) | 68 (32-93) |
<50 years | 55 (28) | 162 (31) | 48 (24) | 36 (7) | 96 (38) | 110 (26) | 45 (18) | 34 (8) |
≥50 years | 145 (73) | 361 (69) | 152 (76) | 487 (93) | 154 (62) | 314 (74) | 205 (82) | 390 (92) |
Node status | ||||||||
N0 | 111 (60) | 324 (69) | 108 (65) | 281 (66) | 161 (72) | 253 (65) | 117 (56) | 251 (71) |
N+ | 75 (40) | 147 (31) | 59 (35) | 143 (34) | 62 (28) | 138 (35) | 91 (44) | 104 (29) |
Missing | 14 | 52 | 33 | 99 | 27 | 33 | 42 | 69 |
Size (mm) | ||||||||
Median (range) | 17 (1-100) | 17 (1-70) | 14 (1-110) | 15 (1-85) | 18 (1-90) | 17 (1-100) | 19 (1-110) | 13 (1-90) |
Missing | 6 | 72 | 10 | 27 | 38 | 32 | 12 | 19 |
Radiotherapy | ||||||||
No | 89 (45) | 180 (35) | 121 (61) | 361 (69) | 96 (39) | 153 (36) | 158 (63) | 283 (67) |
Yes | 111 (56) | 335 (65) | 79 (40) | 160 (31) | 152 (61) | 268 (64) | 91 (37) | 141 (33) |
Missing | 0 | 8 | 0 | 2 | 2 | 3 | 1 | 0 |
Chemotherapy | ||||||||
No | 167 (84) | 478 (93) | 177 (89) | 492 (94) | 227 (92) | 376 (89) | 220 (88) | 402 (95) |
Yes | 33 (17) | 36 (7) | 23 (12) | 29 (6) | 20 (8) | 45 (11) | 29 (12) | 22 (5) |
Missing | 0 | 9 | 0 | 2 | 3 | 3 | 1 | 0 |
Endocrine treatment | ||||||||
No | 148 (74) | 401 (78) | 124 (63) | 304 (59) | 202 (82) | 313 (74) | 146 (59) | 249 (59) |
Yes | 52 (26) | 113 (22) | 74 (37) | 215 (41) | 45 (18) | 108 (26) | 102 (41) | 172 (41) |
Missing | 0 | 9 | 2 | 4 | 3 | 3 | 2 | 3 |
Mode of detection of BC2 | ||||||||
Symptomatic | 57 (31) | 193 (40) | ||||||
Asymptomatic | 129 (69) | 295 (60) | ||||||
Missing | 14 | 35 | ||||||
Time interval to BC2 | ||||||||
Median (range) | 9.1 (0.37-36) | 5.8 (0.30-34) | ||||||
<3 years | 57 (23) | 129 (30) | ||||||
≥3 years | 193 (77) | 295 (70) | ||||||