Table 2 Patient Characteristics 2
Case | Age (y) | Gender | Smoking | Histology | EGFR mutation | PFS to 1st TKI | TKI sequence | Interval from 1st and 2nd | Chemo. after 1st | PS | Response | PFS to 2nd TKI | OS from 2nd TKI |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 50 | F | Current | Ad | NA | 9.8 | G→E | 7.9 | CBDCA+GEM | 1 | PD | 0.9 | 13.1 |
2 | 46 | F | Never | Ad | NA | 11.8 | G→G | 4.5 | DOC | 1 | PR | 6.4 | 24.6 |
3 | 58 | F | Ex | Ad | 19 deletion | 38.4 | G→G | 2.8 | DOC | 1 | SD | 7.3 | 24.1 |
4 | 70 | F | Never | Sq | NA | 10.2 | G→E | 12.8 | GEM | 1 | SD | 1.7 | 4.3 |
5 | 60 | F | Never | Ad | NA | 13 | G→G | 5.4 | GEM | 1 | PD | 1.6 | 2.1 |
6 | 63 | F | Never | Ad | NA | 7.4 | G→E | 2.6 | - | 3 | SD | 3.6 | 7.8 |
7 | 52 | M | Never | Ad | L858R | 5.8 | G→E | 1 | - | 4 | SD | 6.4 | 6.4 |
8 | 51 | M | Current | Ad | NA | 4.3 | G→E | 1.6 | AMR | 3 | PD | 0.6 | 0.9 |
9 | 61 | F | Never | Ad | NA | 8.5 | G→E | 2.3 | VNR | 3 | SD | 2.9 | 4 |
10 | 53 | F | Never | Ad | NA | 12.9 | G→E | 0 | - | 4 | SD | 6.2 | 7.3 |
11 | 54 | M | Current | Ad | 19 deletion | 3.8 | G→E | 7.3 | VNR | 1 | SD | 3.2 | 5 |