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Table 2 Mean follow-up times in years between two successive events (gap times) according to the type of event: locoregional, contralateral breast cancer, metastases, 2nd cancer other than breast or breast cancer death

From: Separate and combined analysis of successive dependent outcomes after breast-conservation surgery: recurrence, metastases, second cancer and death

Event of interest Entry-first event 1st - 2nd event 2nd - 3rd event 3rd - 4th event ANY EVENT after surgery
  Gap time*
(SD)
N
(%)
Gap time
(SD)
N
(%)
Gap time
(SD)
N
(%)
Gap time
(SD)
N
(%)
Gap time
(SD)
N
(%)
Locoregional 5.85
(3.60)
134
(14.6%)
2.57
(2.13)
15
(4.4%)
7.52
-
1
(1.1%)
-
-
0
(0%)
5.53
(3.60)
150
(11.1%)
Contralateral
breast cancer
5.60
(3.45)
63
(6.9%)
1.39
(1.54)
6
(1.8%)
-
-
0
(0%)
-
-
0
(0%)
5.23
(3.53)
69
(5.1%)
Metastases 5.23
(3.29)
117
(12.7%)
1.14
(1.68)
64
(18.9%)
1.10
(1.48)
7
(7.9%)
-
-
0
(0%)
3.68
(3.42)
188
(13.9%)
2nd cancer other than breast 4.71
(2.64)
25
(2.7%)
0.75
(0.71)
3
(0.9%)
1.71
(2.42)
2
(2.3%)
-
-
0
(0%)
4.12
(2.80)
30
(2.2%)
Death from cancer 1.56
(.)
1
(0.1%)
2.14
(1.81)
76
(22.4%)
1.83
(1.62)
52
(59.1%)
1.21
(1.97)
4
(40%)
1.99
(1.71)
133
(9.8%)
Censoring** 10.83
(2.31)
580
(63.1%)
3.41
(3.08)
251
(74.0%)
2.38
(2.20)
78
(88.6%)
1.47
(1.37)
10
(100%)
7.99
(4.51)
919
(67.8%)
TOTAL 8.87
(3.78)
919
(100%)
2.89
(2.94)
339
(100%)
2.32
(2.22)
88
(100%)
1.47
(1.37)
10
(100%)
6.89
(4.51)
1356
(100%)
  1. * Gap time = time between two events
  2. ** censoring by death from other causes or lost to follow-up or alive at study termination