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Table 2 Mean follow-up times in years between two successive events (gap times) according to the type of event: locoregional, contralateral breast cancer, metastases, 2nd cancer other than breast or breast cancer death

From: Separate and combined analysis of successive dependent outcomes after breast-conservation surgery: recurrence, metastases, second cancer and death

Event of interest

Entry-first event

1st - 2nd event

2nd - 3rd event

3rd - 4th event

ANY EVENT after surgery

 

Gap time*

(SD)

N

(%)

Gap time

(SD)

N

(%)

Gap time

(SD)

N

(%)

Gap time

(SD)

N

(%)

Gap time

(SD)

N

(%)

Locoregional

5.85

(3.60)

134

(14.6%)

2.57

(2.13)

15

(4.4%)

7.52

-

1

(1.1%)

-

-

0

(0%)

5.53

(3.60)

150

(11.1%)

Contralateral

breast cancer

5.60

(3.45)

63

(6.9%)

1.39

(1.54)

6

(1.8%)

-

-

0

(0%)

-

-

0

(0%)

5.23

(3.53)

69

(5.1%)

Metastases

5.23

(3.29)

117

(12.7%)

1.14

(1.68)

64

(18.9%)

1.10

(1.48)

7

(7.9%)

-

-

0

(0%)

3.68

(3.42)

188

(13.9%)

2nd cancer other than breast

4.71

(2.64)

25

(2.7%)

0.75

(0.71)

3

(0.9%)

1.71

(2.42)

2

(2.3%)

-

-

0

(0%)

4.12

(2.80)

30

(2.2%)

Death from cancer

1.56

(.)

1

(0.1%)

2.14

(1.81)

76

(22.4%)

1.83

(1.62)

52

(59.1%)

1.21

(1.97)

4

(40%)

1.99

(1.71)

133

(9.8%)

Censoring**

10.83

(2.31)

580

(63.1%)

3.41

(3.08)

251

(74.0%)

2.38

(2.20)

78

(88.6%)

1.47

(1.37)

10

(100%)

7.99

(4.51)

919

(67.8%)

TOTAL

8.87

(3.78)

919

(100%)

2.89

(2.94)

339

(100%)

2.32

(2.22)

88

(100%)

1.47

(1.37)

10

(100%)

6.89

(4.51)

1356

(100%)

  1. * Gap time = time between two events
  2. ** censoring by death from other causes or lost to follow-up or alive at study termination