Figure 1

Pairwise LD for gene variants located within approximately 480 kb at chromosomal position 4q27. The 4q27 region harbors cytokine coding genes IL-2 and IL-21, testis nuclear RNA-binding protein coding gene TENR and a gene coding for a protein of unknown function, KIAA1109. The seven selected SNPs (indicated by rs numbers) in this study display tight linkage across the region. The reference genome assembly used to determine physical SNP position was NCBI Build version 36.3.