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Table 1 Up- and down-regulated genes and their representing functional groups in PC3-AKR1C3 transfectants

From: Elevated AKR1C3 expression promotes prostate cancer cell survival and prostate cell-mediated endothelial cell tube formation: implications for prostate cancer progressioan

Up-regulated genes Down-regulated genes
Cancer, Cellular growth and proliferation Cell death
BEX1 Brain expressed, X-linked 1 CALB1 Calbindin 1, 28 kDa
FBLN1 Fibulin 1 CD70 CD70 molecule
FGD3 FYVE, RhoGEF and PH domain containing 3 DDIT4 DNA-damage-inducible transcript 4
HBEGF Heparin-binding EGF-like growth factor FAM162A  
KLK3 Kallikrein-related peptidase 3 FTH1 Ferritin, heavy polypeptide 1
KLK6 Kallikrein-related peptidase 6 HCLS1 Hematopoietic cell-specific Lyn substrate 1
WNT5B Wingless-type MMTV integration site family, member 5B ID1 Inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
   IL1RN Interleukin 1 receptor antagonist
   LDLR Low density lipoprotein receptor (familial hypercholesterolemia)
   NEFL Neurofilament, light polypeptide 68 kDa
   PERP PERP, TP53 apoptosis effector
   PMAIP1 Phorbol-12-myristate-13-acetate-induced protein 1
   PRDM1 PR domain containing 1, with ZNF domain
   RUNX2 Runt-related transcription factor 2
   SERPINB5 Serpin peptidase inhibitor, clade B (ovalbumin), member 5