Table 1 Up- and down-regulated genes and their representing functional groups in PC3-AKR1C3 transfectants
Up-regulated genes | Down-regulated genes | ||
|---|---|---|---|
Cancer, Cellular growth and proliferation | Cell death | ||
BEX1 | Brain expressed, X-linked 1 | CALB1 | Calbindin 1, 28 kDa |
FBLN1 | Fibulin 1 | CD70 | CD70 molecule |
FGD3 | FYVE, RhoGEF and PH domain containing 3 | DDIT4 | DNA-damage-inducible transcript 4 |
HBEGF | Heparin-binding EGF-like growth factor | FAM162A | Â |
KLK3 | Kallikrein-related peptidase 3 | FTH1 | Ferritin, heavy polypeptide 1 |
KLK6 | Kallikrein-related peptidase 6 | HCLS1 | Hematopoietic cell-specific Lyn substrate 1 |
WNT5B | Wingless-type MMTV integration site family, member 5B | ID1 | Inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| Â | Â | IL1RN | Interleukin 1 receptor antagonist |
| Â | Â | LDLR | Low density lipoprotein receptor (familial hypercholesterolemia) |
| Â | Â | NEFL | Neurofilament, light polypeptide 68 kDa |
| Â | Â | PERP | PERP, TP53 apoptosis effector |
| Â | Â | PMAIP1 | Phorbol-12-myristate-13-acetate-induced protein 1 |
| Â | Â | PRDM1 | PR domain containing 1, with ZNF domain |
| Â | Â | RUNX2 | Runt-related transcription factor 2 |
| Â | Â | SERPINB5 | Serpin peptidase inhibitor, clade B (ovalbumin), member 5 |