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Figure 1 | BMC Cancer

Figure 1

From: Elevated AKR1C3 expression promotes prostate cancer cell survival and prostate cell-mediated endothelial cell tube formation: implications for prostate cancer progressioan

Figure 1

Influence of steroid hormone signaling in PC3-AKR1C3 transfectants. (A) Genes whose expression is altered in PC3-AKR1C3 transfectants were identified to be regulated by 17β-estradiol, androstenediol, or 5α-DHT. Genes that are labeled in red and green represent up- and down-regulated genes, respectively, in PC3-AKR1C3 transfectants as compared to PC3-mock transfectants. The fold changes are reflected by corresponding numbers under the gene names. (B) FST expression can be regulated by AKR1C3-mediated testosterone and/or progesterone metabolism in PC3-AKR1C3 transfectants. The legend for the gene shapes is at lower right corner.

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BMC Cancer

ISSN: 1471-2407

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