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Table 1 Characteristics of study participants, by study

From: Characterization of the association between 8q24 and colon cancer: gene-environment exploration and meta-analysis

  DALS WHI
  Controls Cases Controls Cases
Characteristic n (%) n (%) n (%) n (%)
N 1813 1461 526 526
Gender     
   Male 963 (53.1) 822 (56.3) 0 0
   Female 850 (46.9) 639 (43.7) 526 (100) 526 (100)
Age     
   30-39 40 (2.1) 21 (1.4) 0 0
   40-49 116 (6.4) 86 (5.9) 0 0
   50-59 292 (16.1) 270 (18.5) 72 (13.7) 73 (13.9)
   60-69 622 (34.3) 507 (34.7) 229 (43.5) 229 (43.5)
   70-79 743 (41.0) 577 (39.5) 225 (42.8) 224 (43.6)
Family History of CRC     
   No 1st degree relative 1637 (90.3) 1213 (83.0) 384 (80.5) 381 (77.1)
   ≥1 1st degree relatives 176 (9.7) 248 (17.0) 93 (19.5) 113 (22.9)
Cigarette Smoker     
   Never 852 (47.0) 597 (41.0) 252 (48.2) 233 (44.8)
   Former 715 (39.4) 649 (44.5) 240 (45.9) 252 (48.5)
   Current 246 (13.6) 212 (14.5) 31 (5.9) 35 (6.8)
BMI     
   < 25 720 (39.8) 485 (33.3) 199 (38.3) 186 (35.8)
   ≥25 1090 (60.2) 971 (66.7) 320 (61.7) 334 (64.2)
Physical Activity     
   < 1 hour per week 1089 (60.1) 937 (64.2) 251 (48.3) 255 (49.0)
   ≥1 hours per week 724 (39.9) 523 (35.8) 269 (51.7) 265 (51.0)
NSAID use     
   Not Current User 1098 (60.0) 1018 (69.7) 362 (68.8) 367 (69.8)
   Current User 715 (39.4) 443 (30.3) 164 (31.2) 159 (30.2)
Hormone Replacement Therapy Use    
   Not Current User 503 (69.2) 422 (76.1) 311 (59.2) 345 (65.7)
   Current User 224 (30.8) 133 (23.9) 214 (40.8) 180 (34.3)
Alcohol consumption     
   < 1 drink a week 1025 (56.5) 825 (56.5) 298 (56.8) 324 (62.0)
   ≥1 drinks per week 788 (43.5) 636 (43.5) 227 (43.2) 199 (38.1)
Tumor Stage     
   Localized NA 538 (38.5) NA 212 (40.3)
   Regional NA 702 (50.2) NA 228 (43.4)
   Distant NA 117 (8.4) NA 67 (12.7)
   Missing/Unknown NA 103 (2.9) NA 19 (3.6)
Tumor Site     
   Distal Colon NA 720 (49.3) NA 143 (27.2)
   Proximal Colon NA 705 (48.3) NA 361 (68.6)
   Missing NA 36 (2.5) NA 22 (4.2)
  1. DALS = Diet Activity and Lifestyle Study; WHI = Women's Health Initiative; N = total sample size; CRC = colorectal cancer; BMI = Body mass index; NSAID = Non-steroidal anti-inflammatory drugs