Table 1 Characteristics of study participants, by study
| Â | DALS | WHI | ||
|---|---|---|---|---|
| Â | Controls | Cases | Controls | Cases |
Characteristic | n (%) | n (%) | n (%) | n (%) |
N | 1813 | 1461 | 526 | 526 |
Gender | Â | Â | Â | Â |
   Male | 963 (53.1) | 822 (56.3) | 0 | 0 |
   Female | 850 (46.9) | 639 (43.7) | 526 (100) | 526 (100) |
Age | Â | Â | Â | Â |
   30-39 | 40 (2.1) | 21 (1.4) | 0 | 0 |
   40-49 | 116 (6.4) | 86 (5.9) | 0 | 0 |
   50-59 | 292 (16.1) | 270 (18.5) | 72 (13.7) | 73 (13.9) |
   60-69 | 622 (34.3) | 507 (34.7) | 229 (43.5) | 229 (43.5) |
   70-79 | 743 (41.0) | 577 (39.5) | 225 (42.8) | 224 (43.6) |
Family History of CRC | Â | Â | Â | Â |
   No 1st degree relative | 1637 (90.3) | 1213 (83.0) | 384 (80.5) | 381 (77.1) |
   ≥1 1st degree relatives | 176 (9.7) | 248 (17.0) | 93 (19.5) | 113 (22.9) |
Cigarette Smoker | Â | Â | Â | Â |
   Never | 852 (47.0) | 597 (41.0) | 252 (48.2) | 233 (44.8) |
   Former | 715 (39.4) | 649 (44.5) | 240 (45.9) | 252 (48.5) |
   Current | 246 (13.6) | 212 (14.5) | 31 (5.9) | 35 (6.8) |
BMI | Â | Â | Â | Â |
   < 25 | 720 (39.8) | 485 (33.3) | 199 (38.3) | 186 (35.8) |
   ≥25 | 1090 (60.2) | 971 (66.7) | 320 (61.7) | 334 (64.2) |
Physical Activity | Â | Â | Â | Â |
   < 1 hour per week | 1089 (60.1) | 937 (64.2) | 251 (48.3) | 255 (49.0) |
   ≥1 hours per week | 724 (39.9) | 523 (35.8) | 269 (51.7) | 265 (51.0) |
NSAID use | Â | Â | Â | Â |
   Not Current User | 1098 (60.0) | 1018 (69.7) | 362 (68.8) | 367 (69.8) |
   Current User | 715 (39.4) | 443 (30.3) | 164 (31.2) | 159 (30.2) |
Hormone Replacement Therapy Use | Â | Â | Â | |
   Not Current User | 503 (69.2) | 422 (76.1) | 311 (59.2) | 345 (65.7) |
   Current User | 224 (30.8) | 133 (23.9) | 214 (40.8) | 180 (34.3) |
Alcohol consumption | Â | Â | Â | Â |
   < 1 drink a week | 1025 (56.5) | 825 (56.5) | 298 (56.8) | 324 (62.0) |
   ≥1 drinks per week | 788 (43.5) | 636 (43.5) | 227 (43.2) | 199 (38.1) |
Tumor Stage | Â | Â | Â | Â |
   Localized | NA | 538 (38.5) | NA | 212 (40.3) |
   Regional | NA | 702 (50.2) | NA | 228 (43.4) |
   Distant | NA | 117 (8.4) | NA | 67 (12.7) |
   Missing/Unknown | NA | 103 (2.9) | NA | 19 (3.6) |
Tumor Site | Â | Â | Â | Â |
   Distal Colon | NA | 720 (49.3) | NA | 143 (27.2) |
   Proximal Colon | NA | 705 (48.3) | NA | 361 (68.6) |
   Missing | NA | 36 (2.5) | NA | 22 (4.2) |