|
A. Primary outcome measures
| |
|
Cardiorespiratory fitness
|
Maximum exercise test (peakVO2 )
|
|
Muscular strength
|
30 s sit-to-stand test, maximal handgrip strength
|
|
Fatigue
|
Multidimensional Fatigue Inventory (MFI) [38] and the Fatigue Quality List (FQL) [40] questionnaires
|
|
B. Secondary outcome measures
| |
|
Sociodemographic data
|
Age, education, marital status, living situation, comorbidities and life style variables (e.g. smoking)
|
|
Clinical data
| |
|
Medical history
|
Date of diagnosis, subtype of disease, stage of disease, history of therapy
|
|
Disease status and treatment
|
Response to treatment, progression or relapse of disease and data on any additional treatment will be recorded from medical records
|
|
Adverse events
|
Medical records, reports of the sports physician and physical therapist
|
|
Physical tests
| |
|
Physical examination
|
Height, weight, waist and hip circumferences, four skinfolds (biceps, triceps, suprailiacal and subscapular)
|
|
Body composition and bone mineral density
|
Dual Energy X-ray (DXA) scan
|
|
Questionnaires
| |
|
Health-related quality of life
|
EORTC Quality of Life Questionnaire C30 (EORTC QLQ-C30) [43], EuroQol (EQ5D) [44], EORTC Chemotherapy-induced peripheral neuropathy module (QLQ-CIPN20) [45]
|
|
Physical activity
|
Physical Activity Scale for the Elderly (PASE) [46], Recordings of the Actitrainer accelerometer (Actigraph, Fort Walton Beach Florida, USA)
|
|
Mood disturbance
|
Hospital Anxiety and Depression Scale (HADS) [47, 48]
|
|
Functioning in daily life
|
Impact on Participation and Autonomy (IPA) [49]
|
|
Quality of Sleep
|
Pittsburgh Sleep Quality Index (PSQI) [50]
|
|
Return to work
|
Return to work questionnaire
|
|
Moderating variables
|
Questionnaire about pre-illness lifestyle, current attitudes toward and beliefs about exercise in general
|
|
Satisfaction with the intervention
|
Satisfaction questionnaire
|
|
Cost questionnaires
|
Cost dairies
|
|
Compliance with the exercise program
|
Self-report and objective measures (e.g. attendance, exercise logs, target intensity)
|
