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Table 5 Correlation between HPV-16 expression and clinical characteristics of ESCC patients

From: Comparison of prevalence, viral load, physical status and expression of human papillomavirus-16, -18 and -58 in esophageal and cervical cancer: a case-control study

Characteristics

No.

HPV-16 *

r

P #

  

-

±

+

++

  

Age (years)

       

   53.13 ± 10.05

54

22

12

15

5

0.299

0.028

Lymph-node metastasis

       

   Yes

36

16

8

9

3

0.115

0.408

   No

18

6

4

6

2

  

Cancer grade

       

   I

16

8

3

2

1

0.301

0.027

   II

28

13

8

8

3

  

   III

10

1

1

5

1

  
  1. * indicates positive on immunohistochemistry staining.
  2. # P values for the correlation between HPV-16 expression and clinical characteristics of ESCC patients were calculated by Spearman correlation or Fisher exact test as appropriate.