Table 1 Clinical and immunohistochemical data for leiomyosarcoma and synovial sarcoma patients
Characteristics | Cases | Survivin cytoplasm | Survivin nucleus | |||||
|---|---|---|---|---|---|---|---|---|
IRS | 0-2 | 3-4 | 6-8 | 9-12 | 0-2 | 3-4 | 6-8 | |
Staining | negative | weak | moderate | strong | negative | weak | moderate | |
No. | 50 | 8 | 15 | 19 | 8 | 29 | 10 | 11 |
Sex | ||||||||
Male | 21 | 4 | 6 | 8 | 3 | 14 | 4 | 3 |
Female | 29 | 4 | 9 | 11 | 5 | 15 | 6 | 8 |
Histological subtype | ||||||||
Leiomyosarcoma | 24 | 4 | 9 | 10 | 1 | 12 | 8 | 4 |
Synovial sarcoma | 26 | 4 | 6 | 9 | 7 | 17 | 2 | 7 |
Tumor grade | ||||||||
I | 5 | 1 | 1 | 2 | 1 | 3 | 1 | 1 |
II | 21 | 5 | 2 | 10 | 4 | 11 | 6 | 4 |
III | 24 | 9 | 5 | 7 | 3 | 15 | 3 | 6 |
Tumor stage | ||||||||
stage I | 5 | 0 | 1 | 3 | 1 | 2 | 2 | 1 |
stage II | 22 | 5 | 3 | 11 | 3 | 15 | 2 | 5 |
stage III | 17 | 2 | 8 | 5 | 2 | 9 | 4 | 4 |
stage IV | 6 | 1 | 3 | 0 | 2 | 3 | 2 | 1 |
Complete resection | ||||||||
radical (R0) | 38 | 5 | 11 | 15 | 7 | 23 | 7 | 8 |
not radical (R1) | 12 | 3 | 4 | 4 | 1 | 6 | 3 | 3 |
Localization | ||||||||
extremities | 33 | 6 | 10 | 10 | 7 | 18 | 7 | 8 |
trunc wall | 3 | 0 | 2 | 0 | 1 | 2 | 0 | 1 |
head/neck | 2 | 1 | 0 | 1 | 0 | 2 | 0 | 0 |
abdomen/retro- | 12 | 1 | 3 | 8 | 0 | 7 | 3 | 2 |
peritoneum | ||||||||
Patients follow-up | ||||||||
alive | 18 | 2 | 6 | 7 | 3 | 10 | 6 | 2 |
dead | 32 | 6 | 9 | 12 | 5 | 19 | 4 | 9 |