Prediction and diagnosis of bladder cancer recurrence based on urinary content of hTERT, SENP1, PPP1CA, and MCM5 transcripts

Table 2 Patient and tumor characteristic for patients with recurrent and non-recurrent tumors

		Recurrent and primary	Non-recurrent	P-value (Mann-Whitney)
EORTC	1 year	0.33	0.29	0.12
Recurrence score* N = 99	5 years	0.55	0.51	0.13
EORTC	1 year	0.032	0.029	0.16
Progression score* N = 99	5 years	0.11	0.099	0.16
Age at urine sample (years)		69	71	0.18
Male/female ratio		57/20	35/11
Follow-up time (months)		28	29	0.75
Leucocyte pos/neg ratio		5/68	5/40
BCG or MMC treatment before urine sampling		13	11	0.82
Average pellet size**		1.39	1.41	0.95
Average RNA quality (RIN)		3.70	3.83	0.89
Average RNA conc. (pg/μL)		5995 (32-169186)	7990 (5-117671)	0.0029

* EORTC scores are only calculated for non-muscle invasive tumors. There are 51 urine samples in the non-muscle invasive recurrent group and 48 urine samples in the no-tumor group.

ISSN: 1471-2407