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Table 4 Clinical management of FN based on expert opinion

From: The use of chemotherapy regimens carrying a moderate or high risk of febrile neutropenia and the corresponding management of febrile neutropenia: an expert survey in breast cancer and non-Hodgkin's lymphoma

Drug name

Patients treated among those developing FN (%)a

Total daily dose (mg)

Average duration (days)

Piperacillin + tazobactam

34%

16 000

6.1

Amikacin

26%

1 000 to 1 500

4.1

Ceftazidime

18%

2 625 to 4 000

5

Amoxycillin + clavulanic acid

17%

6 000

5.4

Cefepime

14%

6 000 to 16 000

5.8

Filgrastim

13%

0.3

4.5

Fluconazole

8%

200 to 400

6.5

Ciprofloxacin

7%

0.3

5.5

Procedure name

Patients treated among those developing FN (%)*

Average frequency of procedure

Chest X-ray

80%

1.2

Microbiological tests

78%

2.4

Abdominal echography

7%

1.0

Hospitalization by usage of PP/SP

Patients hospitalized among those developing FN (%)

Average [range] LOS (days)

No G-CSF prophylaxis

48%

4.2 [3-7]

PP

19%

1.5 [1-2]

SP

20%

3.3 [3-7]

  1. Only resources with frequencies >5% are reported. The table is based on oncologists' answers. The participating hematologists reported similar findings (results not shown).
  2. LOS: length of stay
  3. aObtained by multiplying the percentage of experts mentioning the drug/test by the average proportion of patients receiving this drug/test as estimated by these experts.