Figure 4

Differences in metabolic and gene expression profiles of identified groups of luminal A samples. Mean spectra of the A1 (black), A2 (red) and A3 (blue) groups of luminal A tumors are plotted with the significantly different points (p < 0.001) indicated with grey vertical lines. At ppm values with allocated metabolites and significant differences in one group versus the other, the direction of the arrows indicate if the latter group has the highest (up) or lowest (down) mean value. GO-terms that were significantly enriched (fdr < 0.01) in the different groups are indicated for each comparison, calculated using Gene Set Analysis (GSA) on the microarray data.