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Table 3 Association of COX-2 expression with tumor characteristics by tumor receptor status1

From: COX-2 activation is associated with Akt phosphorylation and poor survival in ER-negative, HER2-positive breast cancer

  All tumors ER-negative ER-positive Her2 low Her2 high ER-negative/HER2 high
Spearman rank correlation ρ p-value ρ p ρ p ρ p ρ p ρ p
pAkt Ser473 0.23 <0.001 0.24 0.011 0.22 0.006 0.18 0.024 0.33 0.001 0.50 0.003
pAkt Thr308 0.26 <0.001 0.25 0.009 0.26 0.001 0.23 0.003 0.36 <0.001 0.51 0.003
pCasp9 Ser196 0.30 <0.001 0.31 0.001 0.30 <0.001 0.25 0.001 0.40 <0.001 0.67 <0.001
pBAD Ser136 0.20 0.001 0.26 0.008 0.15 0.063 0.13 0.084 0.31 0.002 0.57 <0.001
CD31 0.05 0.402 0.10 0.302 0.01 0.85 -0.02 0.799 0.19 0.084 0.41 0.021
  1. 1 Spearman's correlation coefficient. Calculated with IHC scores 1-4 (negative, weak, moderate, strong) and continuous data (CD31)