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Table 4 Multivariate Survival Analysis - All-Cause Mortality, by Stage

From: Racial differences in treatment and survival in older patients with diffuse large B-cell lymphoma (DLBCL)

   Stage I-II Stage III-IV
   HR p-value 95% CI HR p-value 95% CI
Age          
  66-< 70 ref     ref    
  70-< 75 1.40 < 0.001 1.16 1.70 1.32 < 0.01 1.12 1.55
  75-< 80 1.72 < 0.0001 1.43 2.07 1.74 < 0.0001 1.48 2.04
  ≥ 80 2.90 < 0.0001 2.44 3.45 2.45 < 0.0001 2.11 2.85
Gender          
  Female ref.        
  Male 1.12 0.02 1.02 1.23 1.06 0.17 0.97 1.16
Race          
  White ref.        
  Black 1.16 0.24 0.91 1.49 1.35 0.01 1.08 1.69
  Other 0.99 0.93 0.83 1.19 1.20 0.04 1.01 1.42
DLBCL histology          
  9680 ref.        
  9684 1.45 0.02 1.07 1.96 1.39 0.02 1.06 1.83
Stage at diagnosis          
  I ref.     N/A    
  II 1.29 < 0.0001 1.17 1.41 N/A    
  III N/A     ref.    
  IV N/A     1.38 < 0.001 1.16 1.66
NCI Comorbidity Index          
  0 ref.        
  1 1.23 < 0.001 1.10 1.38 1.13 0.03 1.01 1.26
  2 1.47 < 0.0001 1.25 1.73 1.38 < 0.0001 1.18 1.61
  ≥3 1.99 < 0.0001 1.65 2.39 1.73 < 0.0001 1.44 2.08
Year of diagnosis          
  2001 ref.        
  2002 0.94 0.40 0.82 1.08 0.80 < 0.01 0.70 0.91
  2003 0.86 0.04 0.75 1.00 0.78 < 0.001 0.68 0.89
  2004 0.88 0.10 0.76 1.02 0.77 < 0.001 0.67 0.88
  2005 0.88 0.09 0.75 1.02 0.75 < 0.0001 0.65 0.86
Percent of 25+ year olds in census tract with some college          
  0-< 25% ref.        
  25-< 50% 1.04 0.47 0.93 1.16 0.97 0.56 0.87 1.08
  ≥50% 0.54 0.09 0.26 1.09 1.28 0.45 0.68 2.42
Percent living in poverty in census tract          
  0-< 5% ref.        
  5-< 7% 1.06 0.43 0.92 1.23 1.02 0.78 0.88 1.18
  7-< 12% 1.00 1.00 0.87 1.14 1.09 0.18 0.96 1.24
  ≥12% 1.21 < 0.01 1.06 1.39 1.12 0.09 0.98 1.27
SEER region          
  CA ref.        
  CT 1.16 0.15 0.95 1.42 1.04 0.75 0.84 1.28
  Detroit 1.10 0.35 0.90 1.33 1.19 0.07 0.99 1.43
  HI 0.71 0.13 0.46 1.11 0.87 0.53 0.57 1.34
  IA 0.91 0.38 0.75 1.12 1.01 0.95 0.84 1.21
  NM 1.09 0.61 0.79 1.49 1.27 0.13 0.93 1.73
  Seattle 0.98 0.87 0.78 1.23 1.03 0.75 0.85 1.25
  UT 1.04 0.75 0.81 1.34 1.01 0.94 0.78 1.31
  Atlanta 1.28 0.12 0.94 1.74 0.82 0.19 0.62 1.10
  Rural GA 0.93 0.86 0.41 2.10 1.09 0.87 0.40 2.96
  KY 1.01 0.91 0.84 1.21 1.27 0.01 1.06 1.51
  LA 1.05 0.65 0.86 1.27 1.06 0.54 0.88 1.29
  NJ 1.26 < 0.01 1.08 1.47 1.04 0.60 0.90 1.21
Lymph node site          
  Nodal ref.        
  Extranodal 1.13 0.01 1.03 1.24 0.94 0.52 0.77 1.14
Other conditions          
  Anemia 1.37 < 0.0001 1.18 1.60 1.25 < 0.01 1.08 1.44
  Neutropenia 1.53 0.35 0.62 3.77 0.59 0.37 0.19 1.87
  Thrombocytopenia 1.23 0.49 0.69 2.19 0.96 0.87 0.61 1.53
  Cardiovascular disease 1.33 < 0.001 1.14 1.54 1.18 0.04 1.01 1.37
  1. HR: Hazard Ratio
  2. N/A: Not Applicable
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