Stage I-II | Stage III-IV | ||||||||
---|---|---|---|---|---|---|---|---|---|
HR | p-value | 95% CI | HR | p-value | 95% CI | ||||
Age | |||||||||
66-< 70 | ref | ref | |||||||
70-< 75 | 1.40 | < 0.001 | 1.16 | 1.70 | 1.32 | < 0.01 | 1.12 | 1.55 | |
75-< 80 | 1.72 | < 0.0001 | 1.43 | 2.07 | 1.74 | < 0.0001 | 1.48 | 2.04 | |
≥ 80 | 2.90 | < 0.0001 | 2.44 | 3.45 | 2.45 | < 0.0001 | 2.11 | 2.85 | |
Gender | |||||||||
Female | ref. | ||||||||
Male | 1.12 | 0.02 | 1.02 | 1.23 | 1.06 | 0.17 | 0.97 | 1.16 | |
Race | |||||||||
White | ref. | ||||||||
Black | 1.16 | 0.24 | 0.91 | 1.49 | 1.35 | 0.01 | 1.08 | 1.69 | |
Other | 0.99 | 0.93 | 0.83 | 1.19 | 1.20 | 0.04 | 1.01 | 1.42 | |
DLBCL histology | |||||||||
9680 | ref. | ||||||||
9684 | 1.45 | 0.02 | 1.07 | 1.96 | 1.39 | 0.02 | 1.06 | 1.83 | |
Stage at diagnosis | |||||||||
I | ref. | N/A | |||||||
II | 1.29 | < 0.0001 | 1.17 | 1.41 | N/A | ||||
III | N/A | ref. | |||||||
IV | N/A | 1.38 | < 0.001 | 1.16 | 1.66 | ||||
NCI Comorbidity Index | |||||||||
0 | ref. | ||||||||
1 | 1.23 | < 0.001 | 1.10 | 1.38 | 1.13 | 0.03 | 1.01 | 1.26 | |
2 | 1.47 | < 0.0001 | 1.25 | 1.73 | 1.38 | < 0.0001 | 1.18 | 1.61 | |
≥3 | 1.99 | < 0.0001 | 1.65 | 2.39 | 1.73 | < 0.0001 | 1.44 | 2.08 | |
Year of diagnosis | |||||||||
2001 | ref. | ||||||||
2002 | 0.94 | 0.40 | 0.82 | 1.08 | 0.80 | < 0.01 | 0.70 | 0.91 | |
2003 | 0.86 | 0.04 | 0.75 | 1.00 | 0.78 | < 0.001 | 0.68 | 0.89 | |
2004 | 0.88 | 0.10 | 0.76 | 1.02 | 0.77 | < 0.001 | 0.67 | 0.88 | |
2005 | 0.88 | 0.09 | 0.75 | 1.02 | 0.75 | < 0.0001 | 0.65 | 0.86 | |
Percent of 25+ year olds in census tract with some college | |||||||||
0-< 25% | ref. | ||||||||
25-< 50% | 1.04 | 0.47 | 0.93 | 1.16 | 0.97 | 0.56 | 0.87 | 1.08 | |
≥50% | 0.54 | 0.09 | 0.26 | 1.09 | 1.28 | 0.45 | 0.68 | 2.42 | |
Percent living in poverty in census tract | |||||||||
0-< 5% | ref. | ||||||||
5-< 7% | 1.06 | 0.43 | 0.92 | 1.23 | 1.02 | 0.78 | 0.88 | 1.18 | |
7-< 12% | 1.00 | 1.00 | 0.87 | 1.14 | 1.09 | 0.18 | 0.96 | 1.24 | |
≥12% | 1.21 | < 0.01 | 1.06 | 1.39 | 1.12 | 0.09 | 0.98 | 1.27 | |
SEER region | |||||||||
CA | ref. | ||||||||
CT | 1.16 | 0.15 | 0.95 | 1.42 | 1.04 | 0.75 | 0.84 | 1.28 | |
Detroit | 1.10 | 0.35 | 0.90 | 1.33 | 1.19 | 0.07 | 0.99 | 1.43 | |
HI | 0.71 | 0.13 | 0.46 | 1.11 | 0.87 | 0.53 | 0.57 | 1.34 | |
IA | 0.91 | 0.38 | 0.75 | 1.12 | 1.01 | 0.95 | 0.84 | 1.21 | |
NM | 1.09 | 0.61 | 0.79 | 1.49 | 1.27 | 0.13 | 0.93 | 1.73 | |
Seattle | 0.98 | 0.87 | 0.78 | 1.23 | 1.03 | 0.75 | 0.85 | 1.25 | |
UT | 1.04 | 0.75 | 0.81 | 1.34 | 1.01 | 0.94 | 0.78 | 1.31 | |
Atlanta | 1.28 | 0.12 | 0.94 | 1.74 | 0.82 | 0.19 | 0.62 | 1.10 | |
Rural GA | 0.93 | 0.86 | 0.41 | 2.10 | 1.09 | 0.87 | 0.40 | 2.96 | |
KY | 1.01 | 0.91 | 0.84 | 1.21 | 1.27 | 0.01 | 1.06 | 1.51 | |
LA | 1.05 | 0.65 | 0.86 | 1.27 | 1.06 | 0.54 | 0.88 | 1.29 | |
NJ | 1.26 | < 0.01 | 1.08 | 1.47 | 1.04 | 0.60 | 0.90 | 1.21 | |
Lymph node site | |||||||||
Nodal | ref. | ||||||||
Extranodal | 1.13 | 0.01 | 1.03 | 1.24 | 0.94 | 0.52 | 0.77 | 1.14 | |
Other conditions | |||||||||
Anemia | 1.37 | < 0.0001 | 1.18 | 1.60 | 1.25 | < 0.01 | 1.08 | 1.44 | |
Neutropenia | 1.53 | 0.35 | 0.62 | 3.77 | 0.59 | 0.37 | 0.19 | 1.87 | |
Thrombocytopenia | 1.23 | 0.49 | 0.69 | 2.19 | 0.96 | 0.87 | 0.61 | 1.53 | |
Cardiovascular disease | 1.33 | < 0.001 | 1.14 | 1.54 | 1.18 | 0.04 | 1.01 | 1.37 |