| |
Stage I-II
|
Stage III-IV
|
---|
| |
HR
|
p-value
|
95% CI
|
HR
|
p-value
|
95% CI
|
---|
Age
| | | | | | | | | |
|
66-< 70
|
ref
| | | |
ref
| | | |
|
70-< 75
|
1.40
|
< 0.001
|
1.16
|
1.70
|
1.32
|
< 0.01
|
1.12
|
1.55
|
|
75-< 80
|
1.72
|
< 0.0001
|
1.43
|
2.07
|
1.74
|
< 0.0001
|
1.48
|
2.04
|
|
≥ 80
|
2.90
|
< 0.0001
|
2.44
|
3.45
|
2.45
|
< 0.0001
|
2.11
|
2.85
|
Gender
| | | | | | | | | |
|
Female
|
ref.
| | | | | | | |
|
Male
|
1.12
|
0.02
|
1.02
|
1.23
|
1.06
|
0.17
|
0.97
|
1.16
|
Race
| | | | | | | | | |
|
White
|
ref.
| | | | | | | |
|
Black
|
1.16
|
0.24
|
0.91
|
1.49
|
1.35
|
0.01
|
1.08
|
1.69
|
|
Other
|
0.99
|
0.93
|
0.83
|
1.19
|
1.20
|
0.04
|
1.01
|
1.42
|
DLBCL histology
| | | | | | | | | |
|
9680
|
ref.
| | | | | | | |
|
9684
|
1.45
|
0.02
|
1.07
|
1.96
|
1.39
|
0.02
|
1.06
|
1.83
|
Stage at diagnosis
| | | | | | | | | |
|
I
|
ref.
| | | |
N/A
| | | |
|
II
|
1.29
|
< 0.0001
|
1.17
|
1.41
|
N/A
| | | |
|
III
|
N/A
| | | |
ref.
| | | |
|
IV
|
N/A
| | | |
1.38
|
< 0.001
|
1.16
|
1.66
|
NCI Comorbidity Index
| | | | | | | | | |
|
0
|
ref.
| | | | | | | |
|
1
|
1.23
|
< 0.001
|
1.10
|
1.38
|
1.13
|
0.03
|
1.01
|
1.26
|
|
2
|
1.47
|
< 0.0001
|
1.25
|
1.73
|
1.38
|
< 0.0001
|
1.18
|
1.61
|
|
≥3
|
1.99
|
< 0.0001
|
1.65
|
2.39
|
1.73
|
< 0.0001
|
1.44
|
2.08
|
Year of diagnosis
| | | | | | | | | |
|
2001
|
ref.
| | | | | | | |
|
2002
|
0.94
|
0.40
|
0.82
|
1.08
|
0.80
|
< 0.01
|
0.70
|
0.91
|
|
2003
|
0.86
|
0.04
|
0.75
|
1.00
|
0.78
|
< 0.001
|
0.68
|
0.89
|
|
2004
|
0.88
|
0.10
|
0.76
|
1.02
|
0.77
|
< 0.001
|
0.67
|
0.88
|
|
2005
|
0.88
|
0.09
|
0.75
|
1.02
|
0.75
|
< 0.0001
|
0.65
|
0.86
|
Percent of 25+ year olds in census tract with some college
| | | | | | | | | |
|
0-< 25%
|
ref.
| | | | | | | |
|
25-< 50%
|
1.04
|
0.47
|
0.93
|
1.16
|
0.97
|
0.56
|
0.87
|
1.08
|
|
≥50%
|
0.54
|
0.09
|
0.26
|
1.09
|
1.28
|
0.45
|
0.68
|
2.42
|
Percent living in poverty in census tract
| | | | | | | | | |
|
0-< 5%
|
ref.
| | | | | | | |
|
5-< 7%
|
1.06
|
0.43
|
0.92
|
1.23
|
1.02
|
0.78
|
0.88
|
1.18
|
|
7-< 12%
|
1.00
|
1.00
|
0.87
|
1.14
|
1.09
|
0.18
|
0.96
|
1.24
|
|
≥12%
|
1.21
|
< 0.01
|
1.06
|
1.39
|
1.12
|
0.09
|
0.98
|
1.27
|
SEER region
| | | | | | | | | |
|
CA
|
ref.
| | | | | | | |
|
CT
|
1.16
|
0.15
|
0.95
|
1.42
|
1.04
|
0.75
|
0.84
|
1.28
|
|
Detroit
|
1.10
|
0.35
|
0.90
|
1.33
|
1.19
|
0.07
|
0.99
|
1.43
|
|
HI
|
0.71
|
0.13
|
0.46
|
1.11
|
0.87
|
0.53
|
0.57
|
1.34
|
|
IA
|
0.91
|
0.38
|
0.75
|
1.12
|
1.01
|
0.95
|
0.84
|
1.21
|
|
NM
|
1.09
|
0.61
|
0.79
|
1.49
|
1.27
|
0.13
|
0.93
|
1.73
|
|
Seattle
|
0.98
|
0.87
|
0.78
|
1.23
|
1.03
|
0.75
|
0.85
|
1.25
|
|
UT
|
1.04
|
0.75
|
0.81
|
1.34
|
1.01
|
0.94
|
0.78
|
1.31
|
|
Atlanta
|
1.28
|
0.12
|
0.94
|
1.74
|
0.82
|
0.19
|
0.62
|
1.10
|
|
Rural GA
|
0.93
|
0.86
|
0.41
|
2.10
|
1.09
|
0.87
|
0.40
|
2.96
|
|
KY
|
1.01
|
0.91
|
0.84
|
1.21
|
1.27
|
0.01
|
1.06
|
1.51
|
|
LA
|
1.05
|
0.65
|
0.86
|
1.27
|
1.06
|
0.54
|
0.88
|
1.29
|
|
NJ
|
1.26
|
< 0.01
|
1.08
|
1.47
|
1.04
|
0.60
|
0.90
|
1.21
|
Lymph node site
| | | | | | | | | |
|
Nodal
|
ref.
| | | | | | | |
|
Extranodal
|
1.13
|
0.01
|
1.03
|
1.24
|
0.94
|
0.52
|
0.77
|
1.14
|
Other conditions
| | | | | | | | | |
|
Anemia
|
1.37
|
< 0.0001
|
1.18
|
1.60
|
1.25
|
< 0.01
|
1.08
|
1.44
|
|
Neutropenia
|
1.53
|
0.35
|
0.62
|
3.77
|
0.59
|
0.37
|
0.19
|
1.87
|
|
Thrombocytopenia
|
1.23
|
0.49
|
0.69
|
2.19
|
0.96
|
0.87
|
0.61
|
1.53
|
|
Cardiovascular disease
|
1.33
|
< 0.001
|
1.14
|
1.54
|
1.18
|
0.04
|
1.01
|
1.37
|
- HR: Hazard Ratio
- N/A: Not Applicable