Factors | Number (%) | Median DFS (months) | P value | |
---|---|---|---|---|
Sex | male | 111 (73.5) | 33.99 | 0.036* |
 | female | 40 (26.5) | 21.13 |  |
Age | <55 years | 74 (49.0) | 21.45 | 0.330 |
 | ≥55 years | 77(51.0) | 31.97 |  |
Smoking status | no | 65 (43.0) | 22.24 | 0.305 |
 | yes | 86 (57.0) | 32.99 |  |
Stage | I | 54 (35.8) | NR# | 0.001* |
 | II | 47 (31.1) | 33.64 |  |
 | III | 50 (33.1) | 15.18 |  |
T stage | T1 | 38 (25.2) | NR# | 0.03 |
 | T2 | 99 (65.5) | 18.76 |  |
 | T3-4 | 14 (9.3) | 38.16 |  |
N stage | N0 | 62 (41.1) | NR# | <0.001* |
 | N1 | 50 (33.1) | 33.64 |  |
 | N2 | 39 (25.8) | 13.37 |  |
Histology | Adenocarcinoma | 59 (39.1) | 17.41 | 0.004* |
 | Non- adenocarcinoma | 92 (60.9) | 48.16 |  |
Surgery method | Wedge resection | 5 (3.3) | 17.41 | 0.958 |
 | Lobectomy | 123 (81.5) | 24.41 |  |
 | Pneumonectomy | 23 (15.2) | 31.15 |  |
Chemotherapy regimens | Docetaxel-containing | 40 (26.5) | 18.60 | 0.523 |
 | Vinorelbine- containing | 40 (26.5) | 48.16 |  |
 | Gemcitabine- containing | 51 (33.8) | 24.58 |  |
 | Paclitaxel- containing | 20 (13.2) | 24.41 |  |
TopIIα | Low expression | 117 (77.5) | 19.38 | 0.012* |
 | High expression | 34 (22.5) | NR |  |
Ki67 | Low expression | 96 (63.6) | 22.24 | 0.517 |
 | High expression | 55 (36.4) | 29.37 |  |