Table 7 Up- and downregulated pathways in metastatic carcinomas when and (GenMAPP analysis)
Dysregulated pathways in metastatic canine mammary tumors | Gene number | Dysregulated pathways in metastatic human breast cancer |
|---|---|---|
up-regulated pathways | Â | Ranking in a meta-analysis[1] |
Cell_cycle | 33 | 1 |
Cell_cycle_G1_to_S_control_reactome | 22 | 2 |
DNA_replication_reactome | 25 | 3 |
Tissue_embryonic_stem_cell | 11 | 6 |
Proteasome degradation | 7 | 7 |
down-regulated pathways | Â | Â |
Striated_muscle_contraction | 8 | 4 |
Focal_adhesion | 11 | / |
IL-6_NetPath_18 | 5 | 6 |