Figure 8
Suppression of miR-31 increased cell invasion. (A) Boyden chamber with 8 μm pore polycarbonate membrane coated with Matrigel was used for the invasion assay. The chamber was stained and analyzed by photography, the stained cells were invasive cells in the lower chamber. (B) The invasive cells increased by 8-fold in HCT-116p53+/+ cell line (p = 0.045), and 2-fold in HCT-116p53-/- cell line (p = 0.009).