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Table 3 Cyclin D2 and PTCH1 expression and promoter hypermethylation analysis in astrocytic cell lines

From: Regulation of sonic hedgehog-GLI1 downstream target genes PTCH1, Cyclin D2, Plakoglobin, PAX6 and NKX2.2 and their epigenetic status in medulloblastoma and astrocytoma

Astrocytic Cell lines Cyclin D2 expression Cyclin D2 Expression after 5'aza+TSA Cyclin D2 promoter hypermethylation analysis by MCA-MSP Cyclin D2 promoter hypermethylation Analysis by MCA-Meth Cyclin D2 Hypermethylation by both techniques No Hypermethylation in Cyclin D2 promoter PTCH1 expression in glioma cell lines PTCH1 promoter hypermethylation by MCA-MSP
U87MG + +   +/-  
A172 - +     -  
LN405 + +     +  
SW1783 - +     -  
T98G - ++   ++  
SW1088 + +     ++  
CCF-STTG-1 - +     ++
GOS-3 - ++   ++  
  1. -: no expression; +: expression; ++: high expression; √: yes