| | |
Cases
|
Controls
| | | |
|---|
| |
Haplotype
|
N
|
F
|
N
|
F
|
OR
|
95%CI
|
P χ2
|
|---|
| |
AAGT
|
284
|
0.47
|
248
|
0.47
|
1
| | |
|
1
|
AAG
C
|
72
|
0.12
|
63
|
0.12
|
0.99
|
0.68-1.45
|
0.92
|
| |
G
A
CC
|
60
|
0.1
|
48
|
0.09
|
1.09
|
0.72-1.62
|
0.68
|
| |
AA
CC
|
54
|
0.09
|
42
|
0.08
|
1.12
|
0.72-1.73
|
0.65
|
| |
G
AG
C
|
6
|
0.01
|
0
|
0
| | |
0.03*
|
| |
Total
|
192
|
0.32
|
153
|
0.29
|
1.09
|
0.83-1.43
|
0.5
|
|
2
|
A
G
GT
|
66
|
0.11
|
53
|
0.1
|
1.08
|
0.72-1.62
|
0.68
|
| |
AA
C
T
|
30
|
0.05
|
26
|
0.05
|
1.00
|
0.58-1.75
|
1
|
| |
G
A
C
T
|
24
|
0.04
|
26
|
0.05
|
0.80
|
0.45-1.44
|
0.46
|
| |
A
GC
T
|
0
|
0
|
5
|
0.01
| | |
0.02*
|
| |
G
AGT
|
0
|
0
|
5
|
0.01
| | |
0.02*
|
| |
Others
|
8
|
0.01
|
12
|
0.02
|
0.58
|
0.23-1.44
|
0.23
|
| |
Total
|
128
|
0.21
|
127
|
0.24
|
0.88
|
0.65-1.18
|
0.4
|
| |
Total
|
604
|
1
|
528
|
1
| | | |
- The haplotype combining the predominant alleles was used as a reference. Group 1 was formed by any haplotype containing the rs5275 C allele and group 2 included all the other haplotypes. The haplotypes with less than 1% frequency (Others) are not listed. The impact on breast cancer risk was calculated for the two groups, considering the Odds Ratio (OR) and the 95% Confidence Interval (95%CI) P: Pearson P-value; N: Number of haplotypes. F: Frequency of haplotypes. * Fisher Exact Probability Test (two-tailed). OR was not calculated because of N = 0.
