Skip to main content

Table 4 Clinical performance of the SHOX2 DNA methylation biomarker with regards to cytology (only from 523 valid samples passing the quality criterion).

From: SHOX2 DNA Methylation is a Biomarker for the diagnosis of lung cancer based on bronchial aspirates

Cytology Result Cases Total Controls Total Test Positive Cases (Sensitivity [%]) Test Negative Controls (Specificity [%])
All 281 242 190 (68%) 230 (95%)
Unknown 187 180 128 (68%) 171 (95%)
Negative 73 62 45 (62%) 59 (95%)
Suspicious 15 0 12 (80%) -
Positive 6 0 5 (83%) -
  1. Among these 523 patients, cytological results were available from 156 patient samples (62 negative controls, 73 negative, 15 suspicious, and 6 positive cases).