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Table 1 Characteristics of the patient population.

From: SHOX2 DNA Methylation is a Biomarker for the diagnosis of lung cancer based on bronchial aspirates

  Total Cases Controls
Age 523 (100%) 281 (100%) 242 (100%)
≤ 50 Years 59 (11%) 15 (5%) 44 (18%)
51-60 Years 110 (21%) 59 (21%) 51 (21%)
>60 Years 344 (66%) 206 (73%) 138 (57%)
Unknown 10 (2%) 1 (0%) 9 (4%)
Median Age 66 67 65
Age Range 23-90 37-90 23-85
Smoking Habits    
Non-smokers 90 (17%) 21 (7%) 69 (29%)
Smokers (Current and Former) 320 (61%) 213 (76%) 107 (44%)
Unknown Smoking Status 113 (22%) 47 (17%) 66 (27%)
Range Packs/Years (Smokers only) 0-171 0-171 0-141
Median Packs/Years (Smokers only) 32 40 10
Mean Packs/Years (Smokers only) 34 42 22
Histology Subtype    
Squamous Cell Carcinoma x 103 (37%) x
Adenocarcinoma x 109 (39%) x
NSCLC NOS x 37 (13%) x
SCLC x 29 (10%) x
Other/Unknow x 3 (1%) x
Stage (UICC)    
I x 59 (21%) x
II x 43 (15%) x
III x 108 (38%) x
IV x 62 (22%) x
Unknown x 9 (3%) x
  1. Clinical data of the 523 analyzed patient samples (281 [54%] Cases, 242 [46%] Controls). 111 samples (68 Saccomanno-fixed cases, 4 fresh-frozen cases, 34 Saccomanno-fixed controls, 5 fresh-frozen controls) failed the sample quality control because their DNA yield was too low. They were excluded from analysis and are not included in this table.