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Table 1 Characteristics of the patient population.

From: SHOX2 DNA Methylation is a Biomarker for the diagnosis of lung cancer based on bronchial aspirates

 

Total

Cases

Controls

Age

523 (100%)

281 (100%)

242 (100%)

≤ 50 Years

59 (11%)

15 (5%)

44 (18%)

51-60 Years

110 (21%)

59 (21%)

51 (21%)

>60 Years

344 (66%)

206 (73%)

138 (57%)

Unknown

10 (2%)

1 (0%)

9 (4%)

Median Age

66

67

65

Age Range

23-90

37-90

23-85

Smoking Habits

   

Non-smokers

90 (17%)

21 (7%)

69 (29%)

Smokers (Current and Former)

320 (61%)

213 (76%)

107 (44%)

Unknown Smoking Status

113 (22%)

47 (17%)

66 (27%)

Range Packs/Years (Smokers only)

0-171

0-171

0-141

Median Packs/Years (Smokers only)

32

40

10

Mean Packs/Years (Smokers only)

34

42

22

Histology Subtype

   

Squamous Cell Carcinoma

x

103 (37%)

x

Adenocarcinoma

x

109 (39%)

x

NSCLC NOS

x

37 (13%)

x

SCLC

x

29 (10%)

x

Other/Unknow

x

3 (1%)

x

Stage (UICC)

   

I

x

59 (21%)

x

II

x

43 (15%)

x

III

x

108 (38%)

x

IV

x

62 (22%)

x

Unknown

x

9 (3%)

x

  1. Clinical data of the 523 analyzed patient samples (281 [54%] Cases, 242 [46%] Controls). 111 samples (68 Saccomanno-fixed cases, 4 fresh-frozen cases, 34 Saccomanno-fixed controls, 5 fresh-frozen controls) failed the sample quality control because their DNA yield was too low. They were excluded from analysis and are not included in this table.