Figure 4

Utility of plasma connective tissue growth factor as a predictor of reduced right ventricular function. Receiver operating characteristic (ROC) curve depicting the ability of plasma connective tissue growth factor (CCN2) levels to predict the presence of reduced right ventricular (RV) function (AUC 0.82 [95% CI 0.72;0.92], p < 0.001). Plasma CCN2 levels ≥ 77 μg/L had 88% sensitivity and 69% specificity for detecting patients with reduced RV function.