Table 4 Results of other studies investigating an escalation of the dose of WBI beyond 30 Gy in patients with brain metastases from a relatively radioresistant tumor.
| Reference | Design | N patients | Tumor type | Median survival |
|---|---|---|---|---|
| Cannady et al. [8] | retrospective | 46 | renal cell carcinoma | 30 Gy: 2.7 mos. >30 Gy: 8.5 mos. |
| Isokangas et al. [18] | retrospective | 60 | malignant melanoma | 30 Gy: 4.1 mos. >30 Gy: 9.6 mos. |
| Present study | retrospective | 164 | various | 30 Gy: 3.3 mos. >30 Gy: 9.5 mos |