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Table 2 Univariate analysis of survival.

From: Prognostic factors for outcomes after whole-brain irradiation of brain metastases from relatively radioresistant tumors: a retrospective analysis

  At 6 months At 12 months  
  (%) (%) P
Tumor type    
Malignant melanoma 32 8  
Renal cell carcinoma 38 30  
Colorectal cancer 26 18 0.08
WBI schedule    
5 × 4 Gy 23 8  
10 × 3 Gy 24 14  
15 × 3/20 × 2 Gy 51 37 <0.001
Age    
≤62 years 38 22  
≥63 years 26 17 0.10
Gender    
Female 26 24  
Male 35 18 0.52
Karnofsky Performance Score    
<70 7 2  
≥70 49 32 <0.001
Number of metastases    
1-3 54 38  
≥4 17 6 <0.001
Extracerebral metastases    
No 57 32  
Yes 20 13 <0.001
Interval from first diagnosis to WBI    
≤24 months 31 16  
≥25 months 33 21 0.30
RPA class    
1 96 61  
2 37 25  
3 8 2 <0.001