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Table 4 Univariate survival analysis according to clinico-pathological variables

From: Comparison of thymidine phosphorylase expression and prognostic factors in gallbladder and bile duct cancer

Variable All patients GB cancer Bile duct cancer
   Median Survival p Median Survival p Median Survival p
Anatomic location GB 22 0.939     
  Bile duct 24      
Well differentiated Yes 99 0.001 . 0.001 85 0.001
  No 18   17   19  
Vascular invasion Positive 13 0.022 12 0.029 13 0.261
  Negative 27   27   26  
Perineural invasion Positive 19 0.001 16 0.029 19 0.005
  Negative 40   30   .  
Lymphatic invasion Positive 18 0.011 16 0.047 18 0.080
  Negative 31   30   31  
Lymph node metastasis Positive 18 0.001 38 0.001 21 0.058
  Negative 32   10   30  
Stage 1 83 0.001 . 0.001 36 0.069
  2 22   20   26  
  3 12   9   13  
  4 5   5   8  
P53 Positive 20 0.210 19 0.409 24 0.374
  Negative 30   30   35  
Cyclin D1 Positve 25 0.890 20 0.943 25 0.962
  Negative 22   21   32  
Survivin Positive 27 0.339 20 0.995 58 0.267
  Negative 22   21   25  
TP Positive 22 0.463 22 0.625 22 0.194
  Negative 21   19   32  
ERCC1 Positive 18 0.241 21 0.903 14 0.073
  Negative 27   20   33  
  1. GB, gallbladder; TP, thymidine phosphorylase; ERCC1, excision repair cross complementing protein 1