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Table 4 Univariate survival analysis according to clinico-pathological variables

From: Comparison of thymidine phosphorylase expression and prognostic factors in gallbladder and bile duct cancer

Variable

All patients

GB cancer

Bile duct cancer

  

Median Survival

p

Median Survival

p

Median Survival

p

Anatomic location

GB

22

0.939

    
 

Bile duct

24

     

Well differentiated

Yes

99

0.001

.

0.001

85

0.001

 

No

18

 

17

 

19

 

Vascular invasion

Positive

13

0.022

12

0.029

13

0.261

 

Negative

27

 

27

 

26

 

Perineural invasion

Positive

19

0.001

16

0.029

19

0.005

 

Negative

40

 

30

 

.

 

Lymphatic invasion

Positive

18

0.011

16

0.047

18

0.080

 

Negative

31

 

30

 

31

 

Lymph node metastasis

Positive

18

0.001

38

0.001

21

0.058

 

Negative

32

 

10

 

30

 

Stage

1

83

0.001

.

0.001

36

0.069

 

2

22

 

20

 

26

 
 

3

12

 

9

 

13

 
 

4

5

 

5

 

8

 

P53

Positive

20

0.210

19

0.409

24

0.374

 

Negative

30

 

30

 

35

 

Cyclin D1

Positve

25

0.890

20

0.943

25

0.962

 

Negative

22

 

21

 

32

 

Survivin

Positive

27

0.339

20

0.995

58

0.267

 

Negative

22

 

21

 

25

 

TP

Positive

22

0.463

22

0.625

22

0.194

 

Negative

21

 

19

 

32

 

ERCC1

Positive

18

0.241

21

0.903

14

0.073

 

Negative

27

 

20

 

33

 
  1. GB, gallbladder; TP, thymidine phosphorylase; ERCC1, excision repair cross complementing protein 1
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