Comparison of thymidine phosphorylase expression and prognostic factors in gallbladder and bile duct cancer

BMC Cancer

Table 3 Immunohistochemical staining for tumors stratified by clinico-pathological variables

Variable	TP		ERCC1		Cyclin D1		Survivin		P53
	No.	p	No.	p	No.	p	No.	p	No.	p
Differentiation
Well	18	0.096	11	0.557	9	0.405	14	0.344	17	0.190
Others	57		28		26		39		51
Vascular invasion
Yes	10	0.112	3	0.383	3	0.592	4	0.495	6	0.459
No	61		32		30		46		60
Perineural invasion
Yes	42	0.171	23	0.087	19	0.528	30	0.258	40	0.222
No	28		11		14		19		25
Lymphatic invasion
Yes	30	0.350	17	0.181	14	0.311	16	0.170	28	0.226
No	41		18		19		34		38
LN metastasis
Yes	32	0.310	19	0.126	14	0.470	24	0.091	18	0.274
No	42		19		21		29		31
T stage
1	7	0.027	2	0.083	3	0.442	10	0.806	8	0.009
2	22		14		10		12		16
3	35		15		17		26		41
4	14		8		5		6		7

TP, thymidine phosphorylase; ERCC1, excision repair cross complementing protein 1

ISSN: 1471-2407