Figure 1From: SERPINB5 and AKAP12-- Expression and promoter methylation of metastasis suppressor genes in pancreatic ductal adenocarcinoma mRNA expression of metastasis suppressor genes. Metastasis suppressor gene expression in PDAC cell lines as fold change of expression in normal pancreatic RNA. Each dot represents a PDAC cell line. Only MAP2K4 and TXNIP show downregulation in PDAC cell lines while most other genes are upregulated. *not detected in some cell lines: KiSS-1 not detected in MIAPaCa-2. MAP2K4 not detected in A818, MPanc 96, PaTu 8902, PaTu 8988S and PaTu 8988T. TIMP3 not detected in A818, MIAPaCa-2, PaTu 8902 and PaTu 8988T. AKAP12 and CD82 mRNA expression correlated to one another (P < 0.005). KiSS-1 and MED23 mRNA expression correlated to one another (P < 0.001).Back to article page