mRNA expression of metastasis suppressor genes. Metastasis suppressor gene expression in PDAC cell lines as fold change of expression in normal pancreatic RNA. Each dot represents a PDAC cell line. Only MAP2K4 and TXNIP show downregulation in PDAC cell lines while most other genes are upregulated. *not detected in some cell lines: KiSS-1 not detected in MIAPaCa-2. MAP2K4 not detected in A818, MPanc 96, PaTu 8902, PaTu 8988S and PaTu 8988T. TIMP3 not detected in A818, MIAPaCa-2, PaTu 8902 and PaTu 8988T. AKAP12 and CD82 mRNA expression correlated to one another (P < 0.005). KiSS-1 and MED23 mRNA expression correlated to one another (P < 0.001).