Genetic and epigenetic characteristics of human multiple hepatocellular carcinoma

BMC Cancer

Table 1 Summary of clinical information and experimental results.

patient	HCC_ID	Clin. Diag.	HBsAg	HCV-Ab	p53	beta-catenin	GMA	common aberration	r
1	2	MC	-	+			2.45	+	0.87
	4
2	6	MC	+	-	R273H	S33C	0	-	0.63
	8
3	10	MC	-	+			2.24	-	0.22
	12				Q129stop
4	14	MC	-	+	R249S		8.49	+	0.7
	16				S183stop, E298stop
5	18	MC	-	+		S33C	3.16	-	0.8
	21
6	102	MC	-	+	Q245C		4.9	-	0.83
	104				R249S	Q34E
7	106	IM	-	+			0	-	0.82
	108
8	110	IM	-	+			8.94	+	0.82
	112
9	114	MC	+	-			14.8	+	0.21
	116
10	26*	MC	-	+			0	-	0.27
	27*
11	29*	IM	-	-		Q34E	2	-	0.9
	30*					V22G,S33S,I35S
12	32*	IM	+	-	R175H		0	-	0.87
	33*
13	35*	MC	-	+	Y163N	D32G	10	+	0.63
	36*					T41I
14	38*	MC	-	+	F278A		14.3	+	0.4
	39*
15	41*	MC	+	-			1.41	-	0.76
	42*

*, tumors dissected at the same operation. Others were sampled at different operations.
GMA, geometric mean of number of chromosomal aberrations; common aberrations, common chromosomal aberrations found in tumors from same patients; r, correlation coefficient of methylation patterns of tumors from same patients.

ISSN: 1471-2407