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Table 3 Thin prep and HPV(+) testing by HC2 or PCR versus biopsy

From: Hybrid capture vs. PCR screening of cervical human papilloma virus infections. Cytological and histological associations in 1270 women

  Biopsy results  
  WNL CIN 1 CIN 2 CIN 3 SCC AdenoCa  
ThinPrep        Total
WNL (HPV pos) # 181 4 0 0 0 0 185
ASCUS 40 58 2 0 1 0 101
LSIL 0 117 2 0 0 0 119
HSIL 0 0 7 3 0 0 10
SCC 0 0 0 0 10 0 10
AdenoCa 0 0 0 0 0 1 1
Total 221 179 11 3 11 1 426#
HPV test-HC2 WNL CIN 1 CIN 2 CIN 3 SCC AdenoCa Total
HC2 + 104 137 8 2 9 0 260
Negative 959 44 3 1 2 1 1010
Total 1063 181 11 3 11 1 1270
(+) HPV test-PCR WNL CIN 1 CIN 2 CIN 3 SCC AdenoCa Total
HPV X 180 46 1 0 0 0 227
HPV 6 10 12 2 0 0 0 24
HPV 11 1 24 2 0 0 0 27
HPV 16 0 4 (3*) (3*) 6 (4*) 0 10
HPV 18 0 13 (6*) 0 1 (3*) 1 15
HPV 31 0 4 (1*) (1*) (2*) 0 4
HPV 33 10 0 (1*) (1*) (3*) 0 10
Multiple HPV types 7 60 6 3 4 0 80
PCR (-) 855 18 0 0 0 0 873
Total 1063 181 11 3 11 1 1270
  1. # Data on 844 women with Thin test within normal limits and no HPV detection or colposcopic lesion that did not undergo biopsy are not shown.
  2. 2 Two women had a colposcopic lesion that on biopsy was CIN 1, with normal pap and no HPV
  3. * Denotes the presence of mixed infections that are summarized under multiple HPV types. All multiple infections associated with > = CIN2 had either HPV 16, 18, 31, 33.