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Table 3 Thin prep and HPV(+) testing by HC2 or PCR versus biopsy

From: Hybrid capture vs. PCR screening of cervical human papilloma virus infections. Cytological and histological associations in 1270 women

 

Biopsy results

 
 

WNL

CIN 1¶

CIN 2

CIN 3

SCC

AdenoCa

 

ThinPrep

      

Total

WNL (HPV pos) #

181

4

0

0

0

0

185

ASCUS

40

58

2

0

1

0

101

LSIL

0

117

2

0

0

0

119

HSIL

0

0

7

3

0

0

10

SCC

0

0

0

0

10

0

10

AdenoCa

0

0

0

0

0

1

1

Total

221

179

11

3

11

1

426#

HPV test-HC2

WNL

CIN 1¶

CIN 2

CIN 3

SCC

AdenoCa

Total

HC2 +

104

137

8

2

9

0

260

Negative

959

44

3

1

2

1

1010

Total

1063

181

11

3

11

1

1270

(+) HPV test-PCR

WNL

CIN 1

CIN 2

CIN 3

SCC

AdenoCa

Total

HPV X

180

46

1

0

0

0

227

HPV 6

10

12

2

0

0

0

24

HPV 11

1

24

2

0

0

0

27

HPV 16

0

4

(3*)

(3*)

6 (4*)

0

10

HPV 18

0

13

(6*)

0

1 (3*)

1

15

HPV 31

0

4

(1*)

(1*)

(2*)

0

4

HPV 33

10

0

(1*)

(1*)

(3*)

0

10

Multiple HPV types

7

60

6

3

4

0

80

PCR (-)

855

18

0

0

0

0

873

Total

1063

181

11

3

11

1

1270

  1. # Data on 844 women with Thin test within normal limits and no HPV detection or colposcopic lesion that did not undergo biopsy are not shown.
  2. ¶2 Two women had a colposcopic lesion that on biopsy was CIN 1, with normal pap and no HPV
  3. * Denotes the presence of mixed infections that are summarized under multiple HPV types. All multiple infections associated with > = CIN2 had either HPV 16, 18, 31, 33.
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BMC Cancer

ISSN: 1471-2407

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