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Table 4 Multivariate analysis of clinical and biological parameters for OS

From: Cytochrome 450 1B1 (CYP1B1) polymorphisms associated with response to docetaxel in Castration-Resistant Prostate Cancer (CRPC) patients

Covariates

 

HR (95% CI)

df

P

Visceral metastasis

yes

3.8 (1.4-10.0)

1

0.008

 

no

1 (Ref.)

  

Anaemia

yes

1.0 (0.2-2.5)

1

0.935

 

no

1 (Ref.)

  

Pre-treatment PSA

≤ median

1 (Ref.)

1

0.242

 

> median

0.64 (0.3-1.4)

  

CYP1B1 G4326C

4326CG+4326CC

1 (Ref.)

1

0.003

 

4326GG

1.7-12.8

  
  1. Abbreviations: Ref., Reference.