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Table 4 Multivariate analysis of clinical and biological parameters for OS

From: Cytochrome 450 1B1 (CYP1B1) polymorphisms associated with response to docetaxel in Castration-Resistant Prostate Cancer (CRPC) patients

Covariates   HR (95% CI) df P
Visceral metastasis yes 3.8 (1.4-10.0) 1 0.008
  no 1 (Ref.)   
Anaemia yes 1.0 (0.2-2.5) 1 0.935
  no 1 (Ref.)   
Pre-treatment PSA ≤ median 1 (Ref.) 1 0.242
  > median 0.64 (0.3-1.4)   
CYP1B1 G4326C 4326CG+4326CC 1 (Ref.) 1 0.003
  4326GG 1.7-12.8   
  1. Abbreviations: Ref., Reference.