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Table 1 Patient characteristics

From: Esophageal cancer in the elderly: an analysis of the factors associated with treatment decisions and outcomes

  All patients (n = 282) Patients without visceral metastasis (n = 220) Patients with visceral metastasis (n = 62)
   Curative treatment (n = 151) BSC
(n = 69)
Palliative treatment (n = 30) BSC
(n = 32)
Age      
year, SD
≥ 75 years
76.5 ± 5.5 74.9 ± 4.1 80.0 ± 6.6* 74.2 ± 4.0 78.2 ± 5.8 **
  145 (51.4%) 62 (41.1%) 50 (72.5%) * 12 (40%) 21 (65.6%)
Gender ratio
(men/women)
216/66 (76.6%) 124/27(82.1%) 38/31 (55.1%) * 27/3 (90%) 27/5 (84.3%)
WHO performance status (n = 260)      
0 39 (15.0%) 35 (23.3%) 0 * 3 (10.0%) 1 (3.8%) **
1 119 (45.8%) 84 (56.0%) 11 (20.4%) 18 (60.0%) 6 (23.1%)
2 93 (35.8%) 31 (20.7%) 38 (70.4%) 8 (26.7%) 16 (61.5%)
3 9 (3.5%) 0 5 (9.3%) 1 (3.3%) 3 (11.5%)
Atkinson dysphagia score (n = 270)      
0 31 (11.5%) 20 (13.2%) 7 (11.3%) * 2 (6.9%) 2 (7.1%)
1 9 (25.5%) 43 (28.5%) 6 (9.7%) 14 (48.3%) 6 (21.4%)
2 129 (47.8%) 65 (43.0%) 39 (62.9%) 10 (34.5%) 15 (53.6%)
3 30 (11.1%) 16 (10.6%) 7 (11.3%) 3 (10.3%) 4 (14.3%)
4 11 (4.1%) 7 (4.6%) 3 (4.8%) 0 1 (3.6%)
Initial weight loss (n = 219, SD) 8.4 ± 7.7 6.7 ± 6.6 12.4 ± 11.3 * 9.0 ± 5.6 13.6 ± 10.0 **
Initial weight loss ≥ 10% 84 (38.4%) 40 (28.4%) 22 (64.7%) * 11 (40.7%) 11 (64.7%)
Initial albumin (n = 148, g/l, SD) 35.2 ± 6.9 37.7 ± 5.4 31.4 ± 8.0 * 35.2 ± 4.8 28.7 ± 6.2 **
Creatinine clearance (n = 172, mL/min, SD) 67.1 ± 24.5 72.4 ± 22.7 52.5 ± 23.3 * 76.1 ± 22.5 60.9 ± 26.4
Charlson score
(n = 254)
     
Mean 1.4 1.3 1.7 1.2 1.6
Charlson score at 0 78 (30.7%) 50 (38.5%) 12 (18.2%) * 8 (28.6%) 8 (26.7%)
  1. n: number of patients, SD: standard deviation, g/l: gram per liter, mL/min: milliter per minute,
  2. BSC: best supportive care, *: p < 0.05 curative treatment vs BSC, **: p < 0.05 palliative treatment vs BSC,
  3. : not available for all patients