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Table 3 Univariate and multivariate analysis of DFI for IMLN recurrence

From: Internal mammary lymph node recurrence: rare but characteristic metastasis site in breast cancer

Factors N Univariate analysis Multivariate analysis
   Median (m) p-value HR 95% CI p-value
Menopausal stastus    0.773 NS
   Premenopausal 55 33     
   Postmenopausal 78 42     
Primary tumor location    0.837 NS
   Areola and inner area 61 38     
   Outer area 72 40     
Tumor size(cm)    0.008* 0.5 0.4- 0.8 0.002*
   ≤2 42 49     
   >2 91 33     
Axillary lymph node    0.070 NS
   negative 62 43     
   positive 71 33     
TNM stage    0.390 NS
   I - II 104 38     
   III 29 29     
ER/PR status    0.020* 0.6 0.4- 0.9 0.006*
   Positive 78 50     
   Negative 55 32     
HER-2 status    0.193 NS
   Positive 29 26     
   Negative 104 42     
Adjuvant chemotherapy    0.113 NS
   Yes 124 36     
   No 9 41     
Adjuvant radiotherapy for T >5 cm    0.018* 0.9 0.6- 1.3 0.463
   Yes 3 56     
   No 4 21     
Adjuvant radiotherapy for ALN4    0.949 NS
   Yes 20 29     
   No 8 26     
  1. * p < 0.05